aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
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<strong>aiv</strong> <strong>infeqcia</strong>/<strong>SidsiT</strong> avadmyofebSi B hepatitis virusiT ko-infeqciis<br />
marTvis saxelmwifo stan<strong>da</strong>rti (protokoli)<br />
1. <strong>da</strong>avadebis /nozologiis/sindromis mokle ganmarteba – B hepatiti<br />
a<strong>da</strong>mianis B hepatitis virusiT gamowveuli infeqciuri <strong>da</strong>avadebaa. <strong>aiv</strong><br />
<strong>infeqcia</strong>/Sidsi ewodeba a<strong>da</strong>mianis imunodeficitis virusiT gamowveul<br />
infeqciur <strong>da</strong>avadebas. orive paTogeniT erTdroulad <strong>da</strong>avadebisas<br />
saubaria <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis <strong>da</strong> B hepatitis virusiT ko<strong>infeqcia</strong>ze.<br />
2.kriteriumebi –<br />
a) <strong>da</strong>ma<strong>da</strong>sturebeli – <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis <strong>da</strong>ma<strong>da</strong>sturebeli<br />
kriteriumebia: <strong>aiv</strong> antisxeulebis arseboba sisxlis SratSi<br />
imunoblotingis meTodiT, <strong>aiv</strong> rnm-is <strong>da</strong>/an <strong>aiv</strong> provirusis<br />
dnm-is aRmoCena sisxlSi polimerizaciis jaWvuri reaqciis<br />
meTodiT; BB hepatitis virusiT <strong>da</strong>avadebis <strong>da</strong>ma<strong>da</strong>sturebeli<br />
kriteriumia HBsAg-is arseboba sisxlis SratSi.<br />
imunofermentuli analizis meTodiT. HBsAg-is arseboba > 6<br />
Tveze meti xangrZlivobiT qronikuli HBV infeqciis<br />
maCvenebelia. qronikuli HBV infeqciis sxva<strong>da</strong>sxva variantis<br />
sadiagnostiko markerebia: HBeAg, Anti-HBe <strong>da</strong> HBV DNA.<br />
b) gamomricxavi – <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis gamomricxavi<br />
kriteriumebia: A<strong>aiv</strong> antisxeulebis ararseboba sisxlis<br />
SratSi imunofermentuli analizis meTodiT, <strong>aiv</strong> rnm-is<br />
<strong>da</strong>/an <strong>aiv</strong> provirus dnm-is ararseboba sisxlSi<br />
polimerizaciis jaWvuri reaqciis meTodiT. B hepatitis<br />
virusiT infeqciis gamomricxavi kriteriumebia: H HBsAg-is <strong>da</strong><br />
Anti-HBc antisxeulebis ararseboba sisxlis SratSi.<br />
3.simptomebi <strong>da</strong> niSnebi<br />
a)<strong>da</strong>ma<strong>da</strong>sturebeli - <strong>aiv</strong> <strong>infeqcia</strong>/Sidss paTognomuri <strong>klinikuri</strong><br />
niSnebi ar gaaCnia, igi miekuTvneba laboratoriulad sadiagnozo<br />
<strong>da</strong>avadebebs. simptomebi<strong>da</strong>n SesaZloa gamovyoT: gaxangrZlivebuli<br />
cxeleba, gaxangrZlivebuli faRaraTi, limfadenopaTia,<br />
aramotivirebuli profuzuli oflianoba, Zlieri saerTo<br />
sisuste, aramotivirebuli wonaSi kleba (1 Tvis ganmavlobaSi<br />
sxeulis wonis 10% an meti), sxva<strong>da</strong>sxva gamonayari kansa <strong>da</strong><br />
lorwovanze, kandidozuri ezofagiti, cns-is atipiuri<br />
<strong>da</strong>zianebebi. B hepatiti mwvave stadiaze SesaZloa usimptomod<br />
mimdinareobs, umetes SemTxvevaSi mwvave B hepatitis dros<br />
avadmyofs aReniSneba zoga<strong>da</strong>d hepatitis niSnebi, rogoricaa:<br />
siyviTle, saerTo sisuste, Sardis gamuqeba, ganavlis gaRiaveba,<br />
zogjer sxeulis temperatutis momateba, diskomforti muclis<br />
RruSi, gulisrevis SegrZneba, Rebineba <strong>da</strong> sxva intoqsikaciis<br />
movlenebi. <strong>da</strong>avadebam 1.4%-Si SesaZloa miiRos fulminanturi<br />
mimdinareoba. <strong>avadmyofTa</strong> 10-15%-Si <strong>da</strong>avadeba qronikul<br />
mimdinareobas Rebulobs <strong>da</strong> qronikuli B hepatiti praqtikulad<br />
xasiaTdeba usimptomo mimdinareobiT, SesaZlebelia gamoxatuli<br />
iyos mxolod zogadi saerTo sisuste.<br />
b) gamomricxavi - qronikul B hepatitis iseve rogorc <strong>aiv</strong><br />
<strong>infeqcia</strong>/Sidsis gamomricxavi simptomebi ar arsebobs, qronikul B<br />
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