aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
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<strong>aiv</strong> <strong>infeqcia</strong>/Sidsis fonze ganviTarebuli toqsoplazmozis marTvis<br />
saxelmwifo stan<strong>da</strong>rti (protokoli)<br />
1.<strong>da</strong>avadebis /nozologiis / sindromis mokle ganmarteba _ <strong>aiv</strong><br />
<strong>infeqcia</strong>/Sidsi ewodeba a<strong>da</strong>mianis imunodeficitis virusiT gamowveul<br />
infeqciur <strong>da</strong>avadebas. <strong>da</strong>avadeba toqsoplazmozis gamomwvevia paraziti<br />
Toxoplasma gondii. <strong>SidsiT</strong> avadmyofebSi toqsoplazma iwvevs Tavis tvinSi<br />
mravlobiTi anTebadi ubnebis warmoqmnas <strong>da</strong> gamovlindeba<br />
encefalitis an diseminirebuli <strong>da</strong>avadebis saxiT.<br />
2.kriteriumebi _<br />
a)<strong>da</strong>ma<strong>da</strong>sturebeli _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis <strong>da</strong>ma<strong>da</strong>sturebeli<br />
kriteriumebia: <strong>aiv</strong> antisxeulebis arseboba sisxlis SratSi<br />
imunoblotingis meTodiT, <strong>aiv</strong> rnm-is raodenobrivad <strong>da</strong>/an <strong>aiv</strong><br />
provirus dnm-is Tvisobrivad aRmoCena sisxlSi polimerizaciis<br />
jaWvuri reaqciis meTodiT. toqsoplazmozis dros Tavis tvinis<br />
MAC an MRI skanirebiT aRmoCndeba mravlobiTi rgoliseburi kerebi.<br />
Tu es meTodebi ar aris xelmisawvdomi diagnozis <strong>da</strong>dgenaSi<br />
gvexmareba serologiuri testebi toqsoplazmis sawinaaRmdegod<br />
gamomuSavebul antisxeulebze (IgG klasis). cerebraluri<br />
toqsoplazmozis mqone pacientebis umravlesobas aReniSneba<br />
Toxoplasma gondii-iT gamowveuli infeqciis ga<strong>da</strong>tanis serologiuri<br />
niSnebi. diagnozs a<strong>da</strong>sturebs Tavis tvinis qsovilis histologiuri<br />
gamokvleva.<br />
b)gamomricxavi _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis gamomricxavi kriteriumebia: <strong>aiv</strong><br />
antisxeulebis ar arseboba sisxlis SratSi imunofermentuli<br />
meTodiT, raodenobrivad <strong>aiv</strong> rnm-is <strong>da</strong>/an Tvisobrivad <strong>aiv</strong> provirus<br />
dnm-is ar arseboba sisxlSi polimerizaciis jaWvuri reaqciis<br />
meTodiT. toqsoplazmozis gamomricxavi kriteriumebia Tavis tvinis<br />
MAC an MRI skanirebiT aRmoCndeba mravlobiTi rgoliseburi kerebis<br />
ar arseboba, negatiuri serologiuri testebi toqsoplazmis<br />
sawinaaRmdegod gamomuSavebul antisxeulebze (IgG klasis).<br />
3.simptomebi <strong>da</strong> niSnebi<br />
a)<strong>da</strong>ma<strong>da</strong>sturebeli _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidss paTognomuri <strong>klinikuri</strong> niSnebi<br />
ar gaaCnia. igi miekuTvneba laboratoriulad sadiagnozo <strong>da</strong>avadebebs.<br />
simptomebi<strong>da</strong>n SeiZleba gamovyoT: gaxangrZlivebuli cxeleba,<br />
gaxangrZlivebuli faRaraTi, limfadenopaTia, aramotivirebuli<br />
profuzuli oflianoba, Zlieri saerTo sisuste, aramotivirebuli wonaSi<br />
kleba (erTi Tvis ganmavlobaSi sxeulis wonis 10% <strong>da</strong> meti), sxva<strong>da</strong>sxva<br />
gamonayari kansa <strong>da</strong> lorwovanze, kandidozuri ezofagiti, cns-is<br />
atipiuri <strong>da</strong>zianebebi <strong>da</strong> sxva. toqsoplazmozis dros saxezea Semdegi<br />
<strong>klinikuri</strong> suraTi: cnobierebis <strong>da</strong>rRveva, cxeleba, krunCxvebi, Tavis<br />
tkivili, kerovani nevrologiuri simptomatika motoruli deficitis,<br />
kraniuli nervis parezis, moZraobis SezRudvis, dismetriis, mxedvelobis<br />
<strong>da</strong>kargvis <strong>da</strong> afaziis CaTvliT.<br />
b)gamomricxavi _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis gamomricxavi simptomebi ar<br />
arsebobs, <strong>aiv</strong> inficirebuli wlebis ganmavlobaSi SeiZleba Civilebs ar<br />
warmoadgendes. toqsoplazmozis gamomricxavi faqtoria Sesabamisi<br />
Civilebisa <strong>da</strong> simptomebis ar arseboba.<br />
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