aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
<strong>aiv</strong> <strong>infeqcia</strong>/Sidsis fonze ganviTarebuli arahojkinis limfomebis<br />
marTvis saxelmwifo stan<strong>da</strong>rti (protokoli)<br />
1.<strong>da</strong>avadebis /nozologiis / sindromis mokle ganmarteba _ <strong>aiv</strong><br />
<strong>infeqcia</strong>/Sidsi ewodeba a<strong>da</strong>mianis imunodeficitis virusiT gamowveul<br />
infeqciur <strong>da</strong>avadebas. arahojkinis lomfomebi limfuri sistemis<br />
avTvisebiani simsivneebia, romlebic Sidsis fonze xSir SemTxvevaSi<br />
asocirebulia epStein-baris virusTan (EBV).<br />
2.kriteriumebi _<br />
a)<strong>da</strong>ma<strong>da</strong>sturebeli _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis <strong>da</strong>ma<strong>da</strong>sturebeli kriteriumebia:<br />
<strong>aiv</strong> antisxeulebis arseboba sisxlis SratSi imunoblotingis meTodiT,<br />
<strong>aiv</strong> rnm-is raodenobrivad <strong>da</strong>/an <strong>aiv</strong> provirus dnm-is Tvisobrivad aRmoCena<br />
sisxlSi polimerizaciis jaWvuri reaqciis meTodiT. arahojkinis<br />
limfomebis diagnozi <strong>da</strong>sturdeba hipereplazirebuli limfuri kvanZis<br />
biofsiiT, histologiuri gamokvleviT.<br />
b)gamomricxavi _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis gamomricxavi kriteriumebia: <strong>aiv</strong><br />
antisxeulebis ar arseboba sisxlis SratSi imunofermentuli meTodiT,<br />
raodenobrivad <strong>aiv</strong> rnm-is <strong>da</strong>/an Tvisobrivad <strong>aiv</strong> provirus dnm-is ar<br />
arseboba sisxlSi polimerizaciis jaWvuri reaqciis meTodiT.<br />
arahojkinis limfomis gamomricxavi kriteriumebia simsivnis<br />
morfologiuri substratis ar arseboba hiperplazirebuli limfuri<br />
kvanZis bioptatSi.<br />
3.simptomebi <strong>da</strong> niSnebi<br />
a)<strong>da</strong>ma<strong>da</strong>sturebeli _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidss paTognomuri <strong>klinikuri</strong> niSnebi<br />
ar gaaCnia. igi miekuTvneba laboratoriulad sadiagnozo <strong>da</strong>avadebebs.<br />
simptomebi<strong>da</strong>n SeiZleba gamovyoT: gaxangrZlivebuli cxeleba,<br />
gaxangrZlivebuli faRaraTi, limfadenopaTia, aramotivirebuli<br />
profuzuli oflianoba, Zlieri saerTo sisuste, aramotivirebuli wonaSi<br />
kleba (erTi Tvis ganmavlobaSi sxeulis wonis 10% <strong>da</strong> meti), sxva<strong>da</strong>sxva<br />
gamonayari kansa <strong>da</strong> lorwovanze, kandidozuri ezofagiti, cns-is<br />
atipiuri <strong>da</strong>zianebebi <strong>da</strong> sxva. arahojkinis limfomebis dros simptomebi<br />
mravalferovania: hiperplazirebuli limfuri kvanZebi SesaZlebelia<br />
palpirdebodes sxva<strong>da</strong>sxva adgilze; cxeleba, wonaSi kleba <strong>da</strong> sisuste<br />
xSiria, Tumca ara aucilebeli; <strong>da</strong>avadebis stadiis gansazRvrisTvis (I-IV)<br />
aucilebelia Semdegi gamokvlevebi: cerebruli, cervikaluri,<br />
Torakaluri <strong>da</strong> abdominaluri kompiuterul-aqsialuri tomografiuli<br />
(CAT) skanireba, Zvlis tvinis <strong>da</strong> Tav-zurg-tvinis siTxis aspiracia <strong>da</strong><br />
gastroskopia.<br />
b)gamomricxavi _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis gamomricxavi simptomebi ar<br />
arsebobs, <strong>aiv</strong> inficirebuli wlebis ganmavlobaSi SeiZleba Civilebs ar<br />
warmoadgendes. arahojkinis limfomis gamomricxavi faqtoria Sesabamisi<br />
Civilebisa <strong>da</strong> simptomebis ar arseboba.<br />
4.diagnostikur _ laboratoriuli testebi <strong>da</strong> specialistTa<br />
konsultaciebi<br />
CD3, CD4, CD8 limfocitebis absoluturi ricxvis gansazRvra, <strong>aiv</strong><br />
virusuli <strong>da</strong>tvirTvis gansazRvra polimerizaciis jaWvuri reaqciis<br />
meTodiT, sisxlis saerTo analizi, RviZlis funqciuri sinjebi,<br />
Tirkmlis funqciuri sinjebi, hiperplazirebuli limfuri kvanZis<br />
biofsia <strong>da</strong> histologiuri gamokvleviT simsivnis morfologiuri<br />
substratis aRmoCena.<br />
162
Change language