aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
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<strong>aiv</strong> <strong>infeqcia</strong>/Sidsis fonze ganviTarebuli atipiuri<br />
mikobaqteriozebis marTvis saxelmwifo stan<strong>da</strong>rti (protokoli)<br />
1. <strong>da</strong>avadebis/nozologiis/sindromis mokle ganmarteba _ <strong>aiv</strong><br />
<strong>infeqcia</strong>/Sidsi ewodeba a<strong>da</strong>mianis imunodeficitis virusiT gamowveul<br />
infeqciur <strong>da</strong>avadebas. atipiuri mikobaqteriozebi ewodeba Mycobacterium<br />
avium complex gamowveul infeqciebs.<br />
2.kriteriumebi _<br />
a)<strong>da</strong>ma<strong>da</strong>sturebeli _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis <strong>da</strong>ma<strong>da</strong>sturebeli kriteriumebia:<br />
<strong>aiv</strong> antisxeulebis arseboba sisxlis SratSi imunoblotingis meTodiT,<br />
<strong>aiv</strong> rnm-is raodenobrivad <strong>da</strong>/an <strong>aiv</strong> provirus dnm-is Tvisobrivad aRmoCena<br />
sisxlSi polimerizaciis jaWvuri reaqciis meTodiT. atipiuri<br />
mikobaqteriebiT gamowveuli infeqciebis diagnozi ismeba <strong>klinikuri</strong><br />
suraTisa <strong>da</strong> laboratoriuli gamokvlevebis mixedviT. misi<br />
<strong>da</strong>ma<strong>da</strong>sturebeli kriteriumia Mycobacterium avium complex -is aRmoCena<br />
specialur nia<strong>da</strong>gze <strong>da</strong>Tesil sisxlSi, ganavalSi, RviZlisa <strong>da</strong> Zvlis<br />
tvinis bioptatSi.<br />
b)gamomricxavi _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis gamomricxavi kriteriumebia: <strong>aiv</strong><br />
antisxeulebis ar arseboba sisxlis SratSi imunofermentuli meTodiT,<br />
raodenobrivad <strong>aiv</strong> rnm-is <strong>da</strong>/an Tvisobrivad <strong>aiv</strong> provirus dnm-is ar<br />
arseboba sisxlSi polimerizaciis jaWvuri reaqciis meTodiT. atipiuri<br />
mikobaqteriebiT gamowveul infeqciebis gamomricxavi kriteriumia<br />
<strong>klinikuri</strong> suraTisa <strong>da</strong> Mycobacterium avium complex -is ar arseboba<br />
specialur nia<strong>da</strong>gze <strong>da</strong>Tesil sisxlSi, ganavalSi, RviZlisa <strong>da</strong> Zvlis<br />
tvinis bioptatSi.<br />
3.simptomebi <strong>da</strong> niSnebi _<br />
a. <strong>da</strong>ma<strong>da</strong>sturebeli _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidss paTognomuri <strong>klinikuri</strong> niSnebi<br />
ar gaaCnia. igi miekuTvneba laboratoriulad sadiagnozo <strong>da</strong>avadebebs.<br />
simptomebi<strong>da</strong>n SeiZleba gamovyoT: gaxangrZlivebuli cxeleba,<br />
gaxangrZlivebuli faRaraTi, limfadenopaTia, aramotivirebuli<br />
profuzuli oflianoba, Zlieri saerTo sisuste, aramotivirebuli wonaSi<br />
kleba (erTi Tvis ganmavlobaSi sxeulis wonis 10% <strong>da</strong> meti), sxva<strong>da</strong>sxva<br />
gamonayari kansa <strong>da</strong> lorwovanze, kandidozuri ezofagiti, cns-is<br />
atipiuri <strong>da</strong>zianebebi <strong>da</strong> sxva. atipiuri mikobaqteriebiT gamowveuli<br />
infeqciebis <strong>da</strong>ma<strong>da</strong>sturebel simptomebs ganekuTvneba cxeleba, wonaSi<br />
kleba, Ramis oflianoba, diarea, ganleva.<br />
b. gamomricxavi _ <strong>aiv</strong> <strong>infeqcia</strong>/Sidsis gamomricxavi simptomebi ar<br />
arsebobs, <strong>aiv</strong> inficirebuli wlebis ganmavlobaSi SeiZleba Civilebs ar<br />
warmoadgendes. atipiuri mikobaqteriebiT gamowveuli infeqciebis<br />
gamomricxavi faqtoria Sesabamisi Civilebisa <strong>da</strong> simptomebis ar arseboba.<br />
4. diagnostikur _ laboratoriuli testebi <strong>da</strong> specialistTa<br />
konsultaciebi<br />
CD3, CD4, CD8 limfocitebis absoluturi ricxvis gansazRvra, <strong>aiv</strong><br />
virusuli <strong>da</strong>tvirTvis gansazRvra polimerizaciis jaWvuri reaqciis<br />
meTodiT, sisxlis saerTo analizi, RviZlis funqciuri sinjebi,<br />
Tirkmlis funqciuri sinjebi, gulmkerdis rentgenologiuri gamokvleva,<br />
Mycobacterium avium complex-is aRmoCena specialur nia<strong>da</strong>gze <strong>da</strong>Tesil<br />
sisxlSi, ganavalSi, RviZlsa <strong>da</strong> Zvlis tvinis bioptatSi.<br />
5. atipuri mikobaqteriozebis <strong>mkurnaloba</strong><br />
antibiotiki doza MmiRebis miRebis mkurnalobis<br />
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