aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
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13<br />
riski maRalia staJirebis periodSi; vaqcinacia un<strong>da</strong> Catardes staJirebaze myofi<br />
medicinis, stomatologiis, saeqTno saqmis, laboratoriuli teqnologiebisa <strong>da</strong><br />
jan<strong>da</strong>cvis sxva profesiebis <strong>da</strong>rgSi.<br />
14 hemodializze myof pacientebSi yovelwliurad un<strong>da</strong> ganisazRvros antisxeulebis<br />
titri, ris mixedviTac Sefasdeba vaqcinaciis <strong>da</strong>matebiTi dozis saWiroeba<br />
bustirebisaTvis; <strong>da</strong>matebiTi doza saWiroa, Tu antisxeulebis titri < 10 mIU/ml.<br />
• armopasuxe pacientebSi rekomendebulia <strong>da</strong>matebiTi dozebi<br />
bustirebisaTvis an vaqcinaciis axali kursi 40µg doziT.<br />
• pacientebs 200/mm 3 -ze naklebi CD4+ limfocitebis ricxviT jer un<strong>da</strong><br />
<strong>da</strong>ewyoT arv <strong>mkurnaloba</strong>; vaqcinacia un<strong>da</strong> ga<strong>da</strong>vdoT klinikurad<br />
SesamCnevi imunuri rekonstituciis miRwevamde, sasurvelia CD4<br />
ujredebis 200/mm 3 -ze metad momatebamde (BII).<br />
4.2.5.2. imunologiuri pasuxi B hepatitis vaqcinaciis mimarT<br />
• pasuxi vaqcinaze <strong>da</strong>mokidebulia vaqcinaciis periodSi CD4+ ujredebis<br />
ricxvze; pasuxi SeiZleba <strong>da</strong>qveiTdes pacientebSi CD4+ ujredebis<br />
500mm 3 -ze naklebi ricxviT.<br />
• B hepatitis vaqcinaciis sruli kursis Catarebisas imunologiuri<br />
pasuxis albaToba <strong>aiv</strong> inficirebul pacientebSi 500/mm 3 -ze maRali CD4+<br />
ujredebis ricxviT 87%-ia, xolo 200-500mm 3 CD4+ ujredebis ricxviT _<br />
mxolod 33%.<br />
• C hepatitisa <strong>da</strong> a<strong>da</strong>mianis imunodeficitis virusebiT ko<strong>infeqcia</strong>m<br />
SesaZloa gamoiwvios B hepatitis vaqcinaciis Semdgomi imunologiuri<br />
pasuxis <strong>da</strong>qveiTeba, aseve B virusis ze<strong>da</strong>piruli antigenis<br />
sawinaaRmdego antisxeulebis titris Semcireba <strong>aiv</strong> monoinfeqciiT<br />
pacientebTan Se<strong>da</strong>rebiT.<br />
4.2.5.3. <strong>aiv</strong> inficirebul pacientTa B hepatitis vaqcinaciis Semdgomi<br />
monitoringi <strong>da</strong> strategia<br />
• B virusis ze<strong>da</strong>piruli antigenis sawinaaRmdego antisxeulebis titri<br />
un<strong>da</strong> ganisazRvros vaqcinaciis <strong>da</strong>mTavrebi<strong>da</strong>n 4 kviraSi.<br />
proteqtoruli antisxeulebis ganuviTareblobis SemTxvevaSi<br />
(HBsas
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