aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
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terminologia<br />
virusuli <strong>da</strong>tvirTva – ewodeba a<strong>da</strong>mianis imunodeficitis virusis (<strong>aiv</strong>-is)<br />
rnm-is raodenobas (koncentracias) plazmis 1 ml-Si;<br />
“fanjara” periodi – ewodeba periods a<strong>da</strong>mianis imunodeficitis virusis<br />
organizmSi SeWri<strong>da</strong>n <strong>aiv</strong>-antisxeulebis gamomuSavebamde;<br />
mwvave retrovirusuli sindromi – ewodeba <strong>aiv</strong>-is organizmSi SeWri<strong>da</strong>n 2-<br />
3 kviris Semdeg ganviTarebul “infeqciuri mononukleozis msgavs<br />
sindroms”, romelic grZeldeba 2-3 kvira, mas mosdevs <strong>klinikuri</strong><br />
gaumjobesebisa <strong>da</strong> serokonversiis periodi;<br />
<strong>klinikuri</strong> gaumjobeseba <strong>da</strong> serokonversia moicavs 2-4 kviras; am<br />
periodSi organizmSi gamomuSavdeba <strong>aiv</strong>-antisxeulebi;<br />
asimptomuri/qronikuli <strong>aiv</strong> <strong>infeqcia</strong> grZeldeba saSualod 8 weli; am<br />
periodis ganmavlobaSi Tan<strong>da</strong>Tan mcirdeba CD4+ limfocitebis<br />
absoluturi raodenoba SratSi <strong>da</strong> izrdeba virusuli <strong>da</strong>tvirTva<br />
plzmaSi;<br />
oportunistuli <strong>infeqcia</strong> ewodeba iseT infeqciebs, romlis gamomwvevi<br />
(baqteria, virusi, paraziti Tu soko) Cveulebriv SeiZleba janmrTeli<br />
a<strong>da</strong>mianis organizmSic binadrobdes <strong>da</strong> ar iwvevdes paTologias <strong>da</strong><br />
mxolod imunokomprometirebul pirebSi gamoiwvios <strong>da</strong>vaadeba.<br />
maRalaqtiuri antiretrovirusuli Terapia (maarT)- (HAART - High Activity<br />
antiretroviral Therapy) –3 an meti antiretrovirusuli preparatis kombinaciis<br />
xangrZlivad gamoyenebaa <strong>aiv</strong> <strong>infeqcia</strong>/<strong>SidsiT</strong> avadmyofebSi, romlis<br />
Sedegad: aRdgeba <strong>da</strong>zianebuli imunuri sistema, xangrZlivad iTrguneba<br />
Sidsis virusis replikacia, xangrZlivdeba avadmyofis sicocxle <strong>da</strong><br />
umjobesdeba pacientis sicocxlis xarisxi.<br />
imunuri rekonstituciis sindromi (irs) – ewodeba paradoqsul reaqcias,<br />
romelic viTardeba antiretrovirusuli mkurnalobis <strong>da</strong>wyebis Semdeg<br />
<strong>da</strong> gamoxateba mdgomareobis gauaresebiT, rac <strong>da</strong>kavSirebulia latentur<br />
mdgomareobaSi myofi ama Tu im oportunistuli paTogenis<br />
gaaqtiurebasTan. imunuri rekonstituciis sindromi aixsneba<br />
antiretrovirusuli Terapiis Sedegad aRdgenili imunuri sistemis<br />
uCveulod mZlavri zemoqmedebiT mag: tuberkulozis mikobaqteriaze.<br />
2. epidemiologia<br />
<strong>aiv</strong> <strong>infeqcia</strong>/Sidsis gavrceleba msoflioSi<br />
<strong>aiv</strong>/Sidsis epidemia kvlav rCeba dinamikur <strong>da</strong> mzardi xasiaTis epidemiad,<br />
romelmac saocari siswrafiT moicva msoflios praqtikulad yvela<br />
kontinenti, yvela qveyana <strong>da</strong> <strong>da</strong>amtkica, rom igi Tanabrad emuqreba yvelas<br />
rasis, sqesis, asakis, erovnebis, ganaTlebisa <strong>da</strong> sarwmunoebis miuxe<strong>da</strong>vad.<br />
jan<strong>da</strong>cvis msoflio organizaciis (janmo) monacemebiT Sidss msoflioSi<br />
sikvdilianobis mizezTa Soris meoTxe adgili ukavia. marTalia,<br />
antiretrovirusuli Terapiis (arT) xelmisawvdomobam <strong>da</strong> efeqturma<br />
profilaqtikurma programebma ganapirobes ganviTarebul qveynebSi<br />
mdgomareobis stabiluroba, magram mTlianad msoflioSi <strong>aiv</strong><br />
inficirebulTa ricxvi mudmivad izrdeba.<br />
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