aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
aiv infeqcia/SidsiT avadmyofTa mkurnaloba da movla (klinikuri ...
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vaqcina xasiaTdeba serokonversiis gansazRvruli doniT. vaqcinaciaze<br />
mopasuxeTa wili <strong>aiv</strong> infeqciis Sidsis stadiaSi progresirebasTan<br />
erTad mcirdeba.<br />
• <strong>aiv</strong> inficirebul simptomur bavSvebsa <strong>da</strong> mozrdilebSi vaqcinaciaze<br />
aRiniSneba suboptimaluri imunologiuri pasuxi. imunuri pasuxi<br />
cocxal <strong>da</strong> <strong>da</strong>xocil antigenebze mcirdeba, ramdena<strong>da</strong>c <strong>aiv</strong> <strong>infeqcia</strong><br />
progresirebs. Tumca, maRali doziT vaqcinaciis SemTxvevaSi imunuri<br />
pasuxi <strong>da</strong> antisxeulebis persistencia <strong>aiv</strong> inficirebul pirebSi<br />
sistemurad Seswavlili ar aris. aRniSnul kontigentSi, SesaZlebelia<br />
gamoyenebul iqnas vaqcinaciis gazrdili doza, an xSiri bustireba.<br />
Tumca am etapze myari rekomen<strong>da</strong>ciebi ar arsebobs.<br />
konkretuli vaqcinisa <strong>da</strong> imunoglobulinis usafrTxoebisa 2 <strong>da</strong><br />
efeqfturobis Sefaseba moicavs aRniSnuli <strong>da</strong>avadebis epidemiologiisa<br />
<strong>da</strong> recipientis imunosupresiis xarisxis gansazRvras. es ukanaskneli<br />
un<strong>da</strong> Sefasdes eqimis mier jan<strong>da</strong>cvis msoflio organizaciis <strong>klinikuri</strong><br />
stadiebis sistemis 3 <strong>da</strong>/an asakobrivi jgufisTvis <strong>da</strong>maxasiaTebeli CD4+<br />
ujredebis ricxvisa <strong>da</strong> procentis mixedviT.<br />
1 BCG vaqcina; difTeriis, tetanusisa <strong>da</strong> yivanaxvelas vaqcina (DTP); OPV; MMR vaqcina;<br />
B hepatitis vaqcina; HiB vaqcina.<br />
2 <strong>aiv</strong> <strong>infeqcia</strong>/<strong>SidsiT</strong> <strong>da</strong>avadebulTa vaqcinirebis usafrTxoebis Sesaxeb informacia<br />
mcirea (Va); vaqcinaciasTan <strong>da</strong>kavSirebuli nebismieri gverdiTi reaqciis Sesaxeb<br />
informacia un<strong>da</strong> miewodoT Sesabamis samsaxurebs; gasaTvaliswinebelia, rom zogierTi<br />
gverdiTi movlena SesaZlebelia gamovlindes xangrZlivi latenturi periodis Semdeg<br />
(DIV).<br />
3 <strong>klinikuri</strong> stadiis Sefasebisas SeiZleba ixelmZRvaneloT antiretrovirusuli<br />
mkurnalobis protokolebiT mozrdilebisa <strong>da</strong> bavSvebisaTvis.<br />
4.2. cocxali atenuirebuli vaqcinebi<br />
4.2.1 BCG vaqcina<br />
BCG vaqcina icavs 2 wlamde asakis bavSvebs diseminirebuli <strong>da</strong> mZime<br />
formis tuberkulozisgan, maT Soris tuberkulozuri meningitisa <strong>da</strong><br />
miliaruli tuberkulozisgan (AI). filtvis tuberkulozis sixSiris<br />
Semcirebis TvalsazrisiT zr<strong>da</strong>srul populaciaSi BCG vaqcinacia<br />
araefeqturia an xasiaTdeba mcire efeqtiT (AI).<br />
ar aris cnobili mcirdeba Tu ara vaqcinis efeqturoba <strong>aiv</strong> inficirebul<br />
bavSvebSi. arsebobs garkveuli monacemebi, rom BCG vaqcinaciis Semdgom<br />
tuberkulinis <strong>da</strong>debiTi testi naklebad xSiria <strong>aiv</strong> inficirebul<br />
bavSvebSi. Tumca aRniSnuli mtkicebulebis sarwmunoeba naTeli ar aris<br />
(Vb). aRwerilia lokaluri garTulebebisa <strong>da</strong> diseminirebuli BCG<br />
infeqciis SemTxvevebi <strong>aiv</strong> inficirebuli bavSvebis vaqcinacii<strong>da</strong>n<br />
ramdenime wlis Semdegac. Tumca prospeqtuli kvlevebiT <strong>aiv</strong> inficirebul<br />
<strong>da</strong> janmrTel axalSobilebSi BCG imunizaciis Semdgomi garTulebebis<br />
riskis mxriv gansxvaveba ar gamovlin<strong>da</strong> (CIII). BCG infeqciis<br />
tubrekulozuri infeqciisagan gansasxvaveblad saWiroa gverdiTi<br />
reaqciebis mWidro monitoringi <strong>aiv</strong> infeqciis maRali prevalentobis<br />
areebSi. Semdgomi kvlevebiT <strong>da</strong>debiTi <strong>da</strong> uaryofiTi mxareebis zust<br />
Sefasebamde BCG vaqcinacia un<strong>da</strong> Catardes mxolod asimptomur <strong>aiv</strong><br />
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