Gli inibitori del recettore IIb/IIIa - Cuorediverona.it
Gli inibitori del recettore IIb/IIIa - Cuorediverona.it
Gli inibitori del recettore IIb/IIIa - Cuorediverona.it
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GP <strong>IIb</strong>/<strong>IIIa</strong> Inhib<strong>it</strong>ion in Diabetics<br />
30-Day Mortal<strong>it</strong>y in Diabetic Patients<br />
Trial N Odds Ratio & 95% Cl Placebo <strong>IIb</strong>/<strong>IIIa</strong><br />
PURSUIT<br />
2163<br />
P=.33<br />
6.1%<br />
5.1%<br />
PRISM<br />
687<br />
P=.07<br />
4.2%<br />
1.8%<br />
PRISM-PLUS<br />
362<br />
P=.17<br />
6.7%<br />
3.6%<br />
GUSTO IV<br />
1677<br />
P=.022<br />
7.8%<br />
5.0%<br />
PARAGON A<br />
412<br />
P=.51<br />
6.2%<br />
4.6%<br />
PARAGON B<br />
1157<br />
P=.93<br />
4.8%<br />
4.9%<br />
Pooled<br />
6458<br />
P=.007<br />
6.2%<br />
4.6%<br />
0 0.5 1 1.5 2<br />
Breslow-Day: P=.50 <strong>IIb</strong>/<strong>IIIa</strong> Better Placebo Better OR=0.74<br />
Roffi M, et al. Circulation. 2001;104:2767-2771. (w<strong>it</strong>h permission)