08.01.2015 Views

Her2/neu Il ruolo del Pertuzumab - Università degli Studi di Torino

Her2/neu Il ruolo del Pertuzumab - Università degli Studi di Torino

Her2/neu Il ruolo del Pertuzumab - Università degli Studi di Torino

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

<strong>Pertuzumab</strong><br />

• Omnitarg / 2C4<br />

• HDIs (Her <strong>di</strong>merization Inhibitors)<br />

• Prodotto nel 1990 dalla Genentech da Fendly<br />

BM* in topi BALB/c immunizzati per <strong>Her2</strong><br />

• MoAb umanizzato<br />

• Genentech – Roche <strong>di</strong> San Francisco<br />

• Cancro <strong>del</strong>la mammella, prostata, polmone,<br />

ovaie e colon-retto<br />

*(Fendly BM et all, Charactirization of murine Monoclonal Antibo<strong>di</strong>es reactive to either the Human Epidermal Growth<br />

Factor Receptor or Her -2/<strong>neu</strong> Gene Product; Cancer Research; 50:1550, 1990)

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!