Appropriatezza diagnostico-terapeutica in oncologia - Quaderni del ...
Appropriatezza diagnostico-terapeutica in oncologia - Quaderni del ... Appropriatezza diagnostico-terapeutica in oncologia - Quaderni del ...
Ministero della Salute Buzdar AU, Valero V, Ibrahim NK, et al. Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: an update of the initial randomized study population and data of additional patients treated with the same regimen. Clin Cancer Res 2007; 13: 228-33 Coates AS, Keshaviah A, Thurlimann B, et al. Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: update of study BIG 1-98. J Clin Oncol 2007; 25: 486-92 Coombs RC, Kilburn LS, Snowdon CF, et al. Survival and safety of exemestane versus tamoxifen after 2-3 years’ tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trial. Lancet 2007; 369: 559-70 Cuppone F, Bria E, Carlini P, et al. Taxanes as primary chemotherapy for early breast cancer. Meta-analysis of randomized trials. Cancer 2008; 113: 238-46 De Laurentiis M, Cancello G, D’Agostino D, et al. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials. J Clin Oncol 2008; 26: 44-53 Early Breast Cancer Trialists’ Collaborative Group. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 365: 1687-717 Fisher B, Dignam J, Wolmark N, et al. Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial. Lancet 1999; 353: 1993-2000 Fisher ER, Redmond C, Fisher B, et al. Pathologic findings from the National Surgical Adjuvant Breast and Bowel Projects (NSABP). Prognostic discriminants for 8-year survival for node-negative invasive breast cancer patients. Cancer 1990; 65 (Suppl. 9): 2121-8 Gianni L, Goldhirsch A, Gelber RD, et al. Update of the HERA trial and the role of 1 year trastuzumab as adjuvant therapy for breast cancer. The Breast 2009; 18 (Suppl. 1): S11 (abstract S25) Gianni L, Semiglazov V, Manikhas GM, et al. Neoadjuvant trastuzumab in locally advanced breast cancer (NOAH): antitumour and safety analysis. J Clin Oncol 2007; 25 (Suppl.): 10S (abstract 532) Gnant M, Mlineritsch B, Schippinger W, et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N Engl J Med 2009; 360: 679-91 Goss PE, Ingle JN, Martino S, et al. Randomized trial of letrozole following tamoxifen as estended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA:17. J Natl Cancer Inst 2005; 97: 1262-71 Hadji P, Body JJ, Apro MS, et al. Practical guidance for the management of aromatase inhibitor-associated bone loss. Ann Oncol 2008; 19: 1407-16 Ingle JN, Dowsett M, Cuzick J, Davies C. Aromatase inhibitors versus tamoxifen as adjuvant therapy for postmenopausal women with estrogen receptor positive breast cancer: meta-analysis of randomized trials of monotherapy and switching strategies. Cancer Res 2009; 69: 12 Jakesz R, Gnant M, Griel R, et al. Tamoxifen and anastrozole as a sequencing strategy in postmenopausal women with hormone-responsive early breast cancer: updated data from the Austrian breast and colorectal cancer study group trial 8. Cancer Res 2009; 69: 14 Joensuu H, Bono P, Kataja V, et al. Update of the FINHER trial based on 5 year of follow-up. The Breast 2009; 18 (Suppl. 1): S10 (abstract S24) Jones SE, Seynaeve C, Hasenburg A, et al. Results of the first planned analysis of the TEAM (tamoxifen exemestane adjuvant multinational) prospective randomized phase III trial in hormone sensitive postmenopausal early breast cancer. San Antonio Breast Cancer Symposium 2008 (abstract 15) Kaufmann M, Jonat W, Hilfrich J, et al. Improved overall survival in postmenopausal women with early breast cancer after anastrozole initiated after treatment with tamoxifen compared with continued tamoxife: the ARNO 95 Study. J Clin Oncol 2007; 25: 2664-70 44
Neoplasie della mammella 3 LHRH agonists in Early Breast Cancer Overview group. Use of luteinising-hormone-releasing hormoneagonists as adjuvant treatment in premenopausal patients with hormone-receptor-positive breast cancer: a meta-analysis of individual patient data from randomised adjuvant trials. Lancet 2007; 369: 1711-23 Lim HS, Ju Lee H, Seok Lee K, et al. Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer. J Clin Oncol 2007; 25: 3837-45 Mamounas E, Jeong J-H, Wickerham L, et al. Benefit from exemestane as extended adjuvant therapy after 5 years of tamoxifen: intention-to-treat analysis of the National Surgical Adjuvant Breast and Bowel project B-33 trial. J Clin Oncol 2008; 26: 1965-71 Mauri D, Pavlidis N, Ioannidis JPA. Neoadjuvant versus adjuvant systemic treatment in breast cancer: a meta-analysis. J Natl Cancer Inst 2005; 97: 188-94 Perez EA, Suman VJ, Davidson N, et al. NCCTG N9831, May 2005 update. Presented at the 45 th annual meeting of the American Society of Clinical Oncology, Orlando, FL, May 16, 2005 Perez EA, Suman VJ, Davidson NE, et al. Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial. J Clin Oncol 2008; 26: 1231-8 Poortmans P. Evidence based radiation oncology: breast cancer. Radiother Oncol 2007; 84: 84-101 Ravdin PM, Cronin KA, Howlader N, et al. The decrease in breast-cancer incidence in 2003 in the United States. New Engl J Med 2007; 356: 1670-4 Recht A, Edge SB, Solin LJ, et al. Postmastectomy radiotherapy. Guidelines of the American Society of Clinical Oncology. J Clin Oncol 2001; 19: 1539-69 Romond E, Perez EA, Bryant J, et al. Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer. N Engl J Med 2005; 353: 1673-84 Schroth W, Antoniadou L, Fritz P, et al. Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes. J Clin Oncol 2007; 25: 5187-93 Slamon D, Eiermann W, Robert N, et al. BCIRG 006: 2 nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC TH) with docetaxel and carboplatin and trastuzumab (TCH) in HER neu positive early breast cancer patients. Breast Cancer Res and Treat 2006; 100 (Suppl. 1) (abstract 52) Smith IE, Dowsett M, Yap Y-S, et al. Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines. J Clin Oncol 2006; 24: 2444-7 The Breast International Group (BIG) 1-98 Collaborative Group. A Comparison of Letrozole and Tamoxifen in Postmenopausal Women with Early Breast Cancer. N Engl J Med 2005; 353: 2747-57 Venturing M, Del Mastro L, Aitini E, et al. Dosedense adjuvant chemotherapy in early breast cancer patients: results from a randomized trial. J Natl Cancer Inst 2005; 97: 1724-33 Zannetti R, Gafà L, Pannelli F, et al. Cancer in Italy 1993-1998: incidence data from cancer registries. Third Volume. Roma: Il Pensiero Scientifico Editore, 2002 45
- Page 10 and 11: Ministero della Salute Nazionale, a
- Page 12 and 13: Ministero della Salute help reach t
- Page 14 and 15: Ministero della Salute 4. Neoplasie
- Page 17 and 18: n. 3, maggio-giugno 2010 Ministero
- Page 19: Principi generali 1 Area di compete
- Page 22 and 23: Ministero della Salute caso, indipe
- Page 24 and 25: Ministero della Salute more (dimens
- Page 26 and 27: Ministero della Salute rurgia torac
- Page 28 and 29: Ministero della Salute Chirurgia de
- Page 30 and 31: Ministero della Salute ment to the
- Page 32 and 33: Ministero della Salute zione protes
- Page 34 and 35: Ministero della Salute 2.6. Carcino
- Page 36 and 37: Ministero della Salute Per consegui
- Page 38 and 39: Ministero della Salute ESMO minimum
- Page 40 and 41: Ministero della Salute (segue) Situ
- Page 42 and 43: Ministero della Salute • T1: tumo
- Page 44 and 45: Ministero della Salute in situ (flu
- Page 46 and 47: Ministero della Salute estesi oltre
- Page 48 and 49: Ministero della Salute adeguato per
- Page 50 and 51: Ministero della Salute quelle in po
- Page 52 and 53: Ministero della Salute premenopausa
- Page 54 and 55: Ministero della Salute bicina e doc
- Page 56 and 57: Ministero della Salute zolo è supe
- Page 58 and 59: Ministero della Salute • Anestesi
- Page 62 and 63: Ministero della Salute Appendice: D
- Page 65 and 66: n. 3, maggio-giugno 2010 Ministero
- Page 67 and 68: Neoplasie della prostata 4 metodo v
- Page 69 and 70: Neoplasie della prostata 4 asse cor
- Page 71 and 72: Neoplasie della prostata 4 Metastas
- Page 73 and 74: Neoplasie della prostata 4 l’appr
- Page 75 and 76: Neoplasie della prostata 4 Recidiva
- Page 77 and 78: Neoplasie della prostata 4 tensione
- Page 79 and 80: Neoplasie della prostata 4 thdrawal
- Page 81 and 82: Neoplasie della prostata 4 PSA dopo
- Page 83 and 84: Neoplasie della prostata 4 tazione
- Page 85 and 86: Neoplasie della prostata 4 juvant h
- Page 87 and 88: Neoplasie della prostata 4 (segue)
- Page 89 and 90: Neoplasie della prostata 4 (segue)
- Page 91: Neoplasie della prostata 4 (segue)
- Page 94 and 95: Ministero della Salute organizzativ
- Page 96 and 97: Ministero della Salute Cancer (UICC
- Page 98 and 99: Ministero della Salute Mucosa Lamin
- Page 100 and 101: Ministero della Salute Hereditary n
- Page 102 and 103: Ministero della Salute 5.5. Trattam
- Page 104 and 105: Ministero della Salute e molecolari
- Page 106 and 107: Ministero della Salute anticorpi an
- Page 108 and 109: Ministero della Salute Un programma
M<strong>in</strong>istero <strong>del</strong>la Salute<br />
Buzdar AU, Valero V, Ibrahim NK, et al. Neoadjuvant<br />
therapy with paclitaxel followed by 5-fluorouracil, epirubic<strong>in</strong>,<br />
and cyclophosphamide chemotherapy and concurrent<br />
trastuzumab <strong>in</strong> human epidermal growth factor<br />
receptor 2-positive operable breast cancer: an update of<br />
the <strong>in</strong>itial randomized study population and data of<br />
additional patients treated with the same regimen. Cl<strong>in</strong><br />
Cancer Res 2007; 13: 228-33<br />
Coates AS, Keshaviah A, Thurlimann B, et al. Five<br />
years of letrozole compared with tamoxifen as <strong>in</strong>itial<br />
adjuvant therapy for postmenopausal women with endocr<strong>in</strong>e-responsive<br />
early breast cancer: update of study<br />
BIG 1-98. J Cl<strong>in</strong> Oncol 2007; 25: 486-92<br />
Coombs RC, Kilburn LS, Snowdon CF, et al. Survival<br />
and safety of exemestane versus tamoxifen after 2-3 years’<br />
tamoxifen treatment (Intergroup Exemestane Study): a<br />
randomised controlled trial. Lancet 2007; 369: 559-70<br />
Cuppone F, Bria E, Carl<strong>in</strong>i P, et al. Taxanes as primary<br />
chemotherapy for early breast cancer. Meta-analysis<br />
of randomized trials. Cancer 2008; 113: 238-46<br />
De Laurentiis M, Cancello G, D’Agost<strong>in</strong>o D, et al.<br />
Taxane-based comb<strong>in</strong>ations as adjuvant chemotherapy<br />
of early breast cancer: a meta-analysis of randomized<br />
trials. J Cl<strong>in</strong> Oncol 2008; 26: 44-53<br />
Early Breast Cancer Trialists’ Collaborative Group. Effects<br />
of chemotherapy and hormonal therapy for early breast<br />
cancer on recurrence and 15-year survival: an overview<br />
of the randomised trials. Lancet 2005; 365: 1687-717<br />
Fisher B, Dignam J, Wolmark N, et al. Tamoxifen <strong>in</strong><br />
treatment of <strong>in</strong>traductal breast cancer: National Surgical<br />
Adjuvant Breast and Bowel Project B-24 randomised<br />
controlled trial. Lancet 1999; 353: 1993-2000<br />
Fisher ER, Redmond C, Fisher B, et al. Pathologic<br />
f<strong>in</strong>d<strong>in</strong>gs from the National Surgical Adjuvant Breast<br />
and Bowel Projects (NSABP). Prognostic discrim<strong>in</strong>ants<br />
for 8-year survival for node-negative <strong>in</strong>vasive breast<br />
cancer patients. Cancer 1990; 65 (Suppl. 9): 2121-8<br />
Gianni L, Goldhirsch A, Gelber RD, et al. Update of<br />
the HERA trial and the role of 1 year trastuzumab as<br />
adjuvant therapy for breast cancer. The Breast 2009;<br />
18 (Suppl. 1): S11 (abstract S25)<br />
Gianni L, Semiglazov V, Manikhas GM, et al. Neoadjuvant<br />
trastuzumab <strong>in</strong> locally advanced breast cancer<br />
(NOAH): antitumour and safety analysis. J Cl<strong>in</strong> Oncol<br />
2007; 25 (Suppl.): 10S (abstract 532)<br />
Gnant M, Ml<strong>in</strong>eritsch B, Schipp<strong>in</strong>ger W, et al. Endocr<strong>in</strong>e<br />
therapy plus zoledronic acid <strong>in</strong> premenopausal<br />
breast cancer. N Engl J Med 2009; 360: 679-91<br />
Goss PE, Ingle JN, Mart<strong>in</strong>o S, et al. Randomized trial<br />
of letrozole follow<strong>in</strong>g tamoxifen as estended adjuvant<br />
therapy <strong>in</strong> receptor-positive breast cancer: updated<br />
f<strong>in</strong>d<strong>in</strong>gs from NCIC CTG MA:17. J Natl Cancer Inst<br />
2005; 97: 1262-71<br />
Hadji P, Body JJ, Apro MS, et al. Practical guidance<br />
for the management of aromatase <strong>in</strong>hibitor-associated<br />
bone loss. Ann Oncol 2008; 19: 1407-16<br />
Ingle JN, Dowsett M, Cuzick J, Davies C. Aromatase<br />
<strong>in</strong>hibitors versus tamoxifen as adjuvant therapy for<br />
postmenopausal women with estrogen receptor positive<br />
breast cancer: meta-analysis of randomized trials of<br />
monotherapy and switch<strong>in</strong>g strategies. Cancer Res<br />
2009; 69: 12<br />
Jakesz R, Gnant M, Griel R, et al. Tamoxifen and<br />
anastrozole as a sequenc<strong>in</strong>g strategy <strong>in</strong> postmenopausal<br />
women with hormone-responsive early breast cancer:<br />
updated data from the Austrian breast and colorectal<br />
cancer study group trial 8. Cancer Res 2009; 69: 14<br />
Joensuu H, Bono P, Kataja V, et al. Update of the<br />
FINHER trial based on 5 year of follow-up. The Breast<br />
2009; 18 (Suppl. 1): S10 (abstract S24)<br />
Jones SE, Seynaeve C, Hasenburg A, et al. Results of the<br />
first planned analysis of the TEAM (tamoxifen exemestane<br />
adjuvant mult<strong>in</strong>ational) prospective randomized<br />
phase III trial <strong>in</strong> hormone sensitive postmenopausal early<br />
breast cancer. San Antonio Breast Cancer Symposium<br />
2008 (abstract 15)<br />
Kaufmann M, Jonat W, Hilfrich J, et al. Improved<br />
overall survival <strong>in</strong> postmenopausal women with early<br />
breast cancer after anastrozole <strong>in</strong>itiated after treatment<br />
with tamoxifen compared with cont<strong>in</strong>ued tamoxife:<br />
the ARNO 95 Study. J Cl<strong>in</strong> Oncol 2007; 25: 2664-70<br />
44