Dr. Lorenzo Gianni - Oncologia Rimini

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CIRG/TORI 010: risultati (ITT) wP+Pl (94) wP + M (91) wP+BV (97) ORR 41.49% 49.45% 51.55% 95%CI 31.4 – 52.1 38.8– 60.1 41.2 – 61.8 mPFS 9.00 9.45 11.50 95%CI 7.4-12.4 8.4-12.1 9.3-15.4 Mackey J, et al. SABCS 2009; #47 SABCS09_GS4_07
CIRG/TORI 010: tossicità Mackey J, et al. SABCS 2009; #47 #SABCS09_GS4_07
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Page 10 and 11: Transduzione del segnale e processi
Page 12 and 13: Effetto inibitori angiogenesi e pos
Page 14 and 15: Metronomic vs conventional scheduli
Page 16 and 17: Rapid Chemotherapy-Induced Acute En
Page 18 and 19: AVF2119g trial CAP 2500 mg CAP + BV
Page 20 and 21: RIBBON-II Brufsky A, Bondarenko IN,
Page 22 and 23: Brufsky A, Bondarenko IN, et al. SA
Page 24 and 25: MO19391 (ATHENA trial) Pierga J, et
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Page 28 and 29: MO19391: ATHENA trial. Elderly vs n
Page 30 and 31: Endpoints di efficacia selezionati:
Page 32 and 33: AVADO trial: disegno, arruolamento
Page 34 and 35: RIBBON-1: PFS Robert N, et al. ASCO
Page 36 and 37: RIBBON-1: ORR e OS Robert N, et al.
Page 38 and 39: N0432:phase II trial of docetaxel w
Page 40 and 41: SABRE: Sunitinib + wP-BV: significa
Page 42 and 43: Bevacizumab + Letrozole PR as best
Page 44 and 45: SUN 1064 study Bergh J. ASCO 2010:
Page 46 and 47: Sunitinib vs Capecitabina nell’AB
Page 50 and 51: Sorafenib: studio IIb randomizzato,
Page 52 and 53: SOLTI-0701: studio IIb randomizzato
Page 54 and 55: Baselga J, et al. SABCS 2009. #45 S
Page 56 and 57: Sicurezza BV in pz con metastasi SN
Page 58 and 59: Complicanze chirurgiche BV in neoad
Page 60 and 61: Complicazioni chirurgiche: non sign
Page 62 and 63: Quali ragioni per beneficio < alle
Page 64: Terapie antiangiogenetiche nel ca m

Dr. Lorenzo Gianni - Oncologia Rimini

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