Rapporto annuale 2007 - Istituto di Ricerche Farmacologiche Mario ...

Rapporto annuale 2007 - Istituto di Ricerche Farmacologiche Mario ... Rapporto annuale 2007 - Istituto di Ricerche Farmacologiche Mario ...

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IRFMN D'Incalci M., Brunelli D., Marangon E., Simone M., Tavecchio M., Gescher A., Mantovani A. Modulation of gene transcription by natural products. A viable anticancer strategy? Current Pharmaceutical Design 2007; 13: 2744-2750. Di Francesco A.M., Meco D., Torella A.R., Barone G., D'Incalci M., Pisano C., Carminati P., Riccardi R. The novel atypical retinoid ST1926 is active in ATRA resistant neuroblastoma cells acting by a different mechanism. Biochem Pharmacol 2007; 73: 643-655. Bertele' V., Banzi R., Capasso F., Tafuri G., Trotta F., Apolone G., Garattini S. Haematological anticancer drugs in Europe: any added value at the time of approval? Eur J Clin Pharmacol 2007; 63: 713-719. Grassi R., Lombardi G., Reginelli A., Capasso F., Romano F., Floriani I., Colacurci N. Coccygeal movement: Assessment with dynamic MRI. Eur J Radiol 2007; 61: 473-479. Torri V., Floriani I., Poli D., European Glaucoma Prevention Study Group (EGPS). Central corneal thickness in the European Glaucoma Prevention Study. Ophthalmology 2007; 114: 454-459. Gambacorti Passerini C., Tornaghi L, Marangon E., Franceschino A., Pogliani E., D'Incalci M., Zucchetti M. Imatinib concentrantrations in human milk. Blood 2007; 109: 1790 Ruzzo A., Graziano F., Loupakis F., Rulli E., Canestrari E., Santini D., Catalano V., Ficarelli R., Maltese P., Bisonni R., Masi G., Schiavon G., Giordani P., Giustini L., Falcone A., Tonini G., Silva R., Mattioli R., Floriani I., Magnani M. Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy. J Clin Oncol 2007; 25: 1247-1254. European Glaucoma Prevention Study Group (EGPS), Torri V., Floriani I., Rulli E., Poli D. Predictive factors for open-angle glaucoma among patients with ocular hypertension in the European Glaucoma Prevention Study. Ophthalmology 2007; 114: 3-9. Grosso F., Jones R.L., Demetri G.D., Judson I.R., Blay J-Y., Le Cesne A., Sanfilippo R., Casieri P., Collini P., Dileo P., Spreafico C., Stacchiotti S., Tamborini E., Tercero J.C., Jimeno J., D'Incalci M., Gronchi A., Fletcher J.A., Pilotti S., Casali P.G. Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol 2007; 8: 595-602. Zangrossi S., Marabese M., Broggini M., Giordano R., D'Erasmo M., Montelatici E., Intini D., Neri A., Pesce M., Rebulla P., Lazzari L. Oct-4 expression in adult human differentiated cells challenges its role as a pure stem cell marker. Stem Cells 2007; 25: 1675-1680. Martinelli M., Bonezzi K., Riccardi E., Kuhn E., Frapolli R., Zucchetti M., Ryan A.J., Taraboletti G., Giavazzi R. Sequence dependent antitumor efficacy of the vascular disrupting agent ZD6126 in combination with paclitaxel Br J Cancer 2007; 97: 888-894. Giavazzi R., Bani M.R., Taraboletti G. Tumor-host interaction in the optimization of paclitaxelbased combination therapies with vascular targeting compounds. Cancer Metastasis Rev 2007; 26: 481-488. Marabese M., Vikhanskaya F., Broggini M. p73: A chiaroscuro gene in cancer. Eur J Cancer 2007; 43: 1361-1372. 29 RAPPORTO ATTIVITA’ 2007

IRFMN Damia G., D'Incalci M. Targeting DNA repair as a promising approach in cancer therapy. Eur J Cancer 2007; 43: 1791-1801. Dolfini E., Roncoroni L., Dogliotti E., Sala G., Erba E., Sacchi N., Ghidoni R. Resveratrol impairs the formation of MDA-MB-231 multicellular tumor spheroids concomitant with ceramide accumulation. Cancer Lett 2007; 249: 143-147. Apolone G., Mosconi P. Techniques for assessing the quality of life with a particular emphasis on physical exercise. Springer-Verlag Italia, Milano, 2007; 183-190. Mosconi P., Satolli R., Colombo C., Liberati A., Donati S., Mele A. Hormone replacement therapy and information: in Italy a Consensus Conference to help woman decision. BMJ 2007. Malesci A., Laghi L., Bianchi P., Delconte G., Randolph A., Torri V., Carnaghi C., Doci R., Rosati R., Montorsi M., Roncalli M., Gennari L., Santoro A. Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancer. Clin Cancer Res 2007; 13: 3831-3839. Miglior S., Torri V., Zeyen T., Pfeiffer N., Vaz J.C., Adamsons I., European Glaucoma Prevention Study Group (EGPS) Intercurrent factors associated with the development of openangle glaucoma in the European Glaucoma Prevention Study. Am J Ophthalmol 2007; 144: 266-275. Ubezio P., Lupi M., Matera G. Antiproliferative activity of cisplatin detected by CFSE in p53- proficient and p53-deficient cells. Immunol Invest 2007; 36: 847-859. Paulis M., Bensi M., Orioli D., Mondello C., Mazzini G., D’Incalci M., Falcioni C., Radaelli E., Erba E., Raimondi E., De Carli L. Transfer of a Human Chromosomal Vector from a Hamster Cell Line to a Mouse Embryonic Stem Cell Line. Stem Cell 2007; 25: 2543-2550. SELEZIONE PUBBLICAZIONI DIVULGATIVE APPARSE NELL'ANNO 2007 Apolone G, Colombo Cinzia Il dolore non necessario Partecipa Salute 2007 Apolone G, Mosconi P Le agenzie regolatorie: FDA, EMEA e AIFA In : La dispensa di PartecipaSalute, 2007; 101-107 Apolone G Il dolore nel paziente con cancro: attività in corso e primi risultati Cancer Aging 2007 5 : s10-s12 Mosconi P, Colombo Cinzia Quale informazione per la donna in menopausa sulla terapia ormonale sostitutiva? Rispondere 30 RAPPORTO ATTIVITA’ 2007

IRFMN<br />

D'Incalci M., Brunelli D., Marangon E., Simone M., Tavecchio M., Gescher A., Mantovani A.<br />

Modulation of gene transcription by natural products. A viable anticancer strategy? Current<br />

Pharmaceutical Design <strong>2007</strong>; 13: 2744-2750.<br />

Di Francesco A.M., Meco D., Torella A.R., Barone G., D'Incalci M., Pisano C., Carminati P.,<br />

Riccar<strong>di</strong> R. The novel atypical retinoid ST1926 is active in ATRA resistant neuroblastoma cells<br />

acting by a <strong>di</strong>fferent mechanism. Biochem Pharmacol <strong>2007</strong>; 73: 643-655.<br />

Bertele' V., Banzi R., Capasso F., Tafuri G., Trotta F., Apolone G., Garattini S. Haematological<br />

anticancer drugs in Europe: any added value at the time of approval? Eur J Clin Pharmacol<br />

<strong>2007</strong>; 63: 713-719.<br />

Grassi R., Lombar<strong>di</strong> G., Reginelli A., Capasso F., Romano F., Floriani I., Colacurci N.<br />

Coccygeal movement: Assessment with dynamic MRI. Eur J Ra<strong>di</strong>ol <strong>2007</strong>; 61: 473-479.<br />

Torri V., Floriani I., Poli D., European Glaucoma Prevention Study Group (EGPS). Central<br />

corneal thickness in the European Glaucoma Prevention Study. Ophthalmology <strong>2007</strong>; 114:<br />

454-459.<br />

Gambacorti Passerini C., Tornaghi L, Marangon E., Franceschino A., Pogliani E., D'Incalci M.,<br />

Zucchetti M. Imatinib concentrantrations in human milk. Blood <strong>2007</strong>; 109: 1790<br />

Ruzzo A., Graziano F., Loupakis F., Rulli E., Canestrari E., Santini D., Catalano V., Ficarelli<br />

R., Maltese P., Bisonni R., Masi G., Schiavon G., Giordani P., Giustini L., Falcone A., Tonini<br />

G., Silva R., Mattioli R., Floriani I., Magnani M. Pharmacogenetic profiling in patients with<br />

advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy. J Clin Oncol<br />

<strong>2007</strong>; 25: 1247-1254.<br />

European Glaucoma Prevention Study Group (EGPS), Torri V., Floriani I., Rulli E., Poli D.<br />

Pre<strong>di</strong>ctive factors for open-angle glaucoma among patients with ocular hypertension in the<br />

European Glaucoma Prevention Study. Ophthalmology <strong>2007</strong>; 114: 3-9.<br />

Grosso F., Jones R.L., Demetri G.D., Judson I.R., Blay J-Y., Le Cesne A., Sanfilippo R., Casieri<br />

P., Collini P., Dileo P., Spreafico C., Stacchiotti S., Tamborini E., Tercero J.C., Jimeno J.,<br />

D'Incalci M., Gronchi A., Fletcher J.A., Pilotti S., Casali P.G. Efficacy of trabecte<strong>di</strong>n<br />

(ecteinasci<strong>di</strong>n-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet<br />

Oncol <strong>2007</strong>; 8: 595-602.<br />

Zangrossi S., Marabese M., Broggini M., Giordano R., D'Erasmo M., Montelatici E., Intini D.,<br />

Neri A., Pesce M., Rebulla P., Lazzari L. Oct-4 expression in adult human <strong>di</strong>fferentiated cells<br />

challenges its role as a pure stem cell marker. Stem Cells <strong>2007</strong>; 25: 1675-1680.<br />

Martinelli M., Bonezzi K., Riccar<strong>di</strong> E., Kuhn E., Frapolli R., Zucchetti M., Ryan A.J.,<br />

Taraboletti G., Giavazzi R. Sequence dependent antitumor efficacy of the vascular <strong>di</strong>srupting<br />

agent ZD6126 in combination with paclitaxel Br J Cancer <strong>2007</strong>; 97: 888-894.<br />

Giavazzi R., Bani M.R., Taraboletti G. Tumor-host interaction in the optimization of paclitaxelbased<br />

combination therapies with vascular targeting compounds. Cancer Metastasis Rev <strong>2007</strong>;<br />

26: 481-488.<br />

Marabese M., Vikhanskaya F., Broggini M. p73: A chiaroscuro gene in cancer. Eur J Cancer<br />

<strong>2007</strong>; 43: 1361-1372.<br />

29<br />

RAPPORTO ATTIVITA’ <strong>2007</strong>

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