Rapporto annuale 2007 - Istituto di Ricerche Farmacologiche Mario ...
Rapporto annuale 2007 - Istituto di Ricerche Farmacologiche Mario ...
Rapporto annuale 2007 - Istituto di Ricerche Farmacologiche Mario ...
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IRFMN<br />
dal 1999 Visiting Professor, Department of Me<strong>di</strong>cine, New York Me<strong>di</strong>cal College, Valhalla, NY,<br />
USA<br />
1981-1983 Car<strong>di</strong>ology Fellow (Robert E. Kates Laboratory), Stanford University Me<strong>di</strong>cal Center, CA,<br />
USA<br />
1973-1990 Ricercatore presso il Laboratorio <strong>di</strong> Farmacologia Clinica, <strong>Istituto</strong> <strong>di</strong> <strong>Ricerche</strong><br />
<strong>Farmacologiche</strong> “<strong>Mario</strong> Negri” <strong>di</strong> Milano<br />
Principali pubblicazioni<br />
• Latini R, Maggioni AP, Peri G, Gonzini L, Lucci D, Mocarelli P, Vago L, Pasqualini F, Signorini S, Soldateschi D, Tarli<br />
L, Schweiger C, Fresco C, Cecere R, Tognoni G, Mantovani A, LATIN Investigators. Prognostic significance of the long<br />
pentraxin PTX3 in acute myocar<strong>di</strong>al infarction. Circulation 2004; 110: 2349-2354<br />
• Corada M, Chimenti S, Cera M R, Vinci M, Salio M, Fiordaliso F, De Angelis N, Villa A, Bossi M, Staszewsky L,<br />
Vecchi A, Parazzoli D, Motoike T, Latini R, Dejana E. Junctional adhesion molecule-A-deficient polymorphonuclear<br />
cells show reduced <strong>di</strong>apedesis in peritonitis and heart ischemia-reperfusion injury. Proc Natl Acad Sci USA 2005; 102:<br />
10634-10639<br />
• Galli D, Innocenzi A, Staszewsky L, Zanetta L, Sampaolesi M, Bai A, Martinoli E, Carlo E, Balconi G, Fiordaliso F,<br />
Chimenti S, Cusella G, Dejana E, Cossu G, Latini R. Mesoangioblasts, vessel-associated multipotent stem cells, repair<br />
the infarcted heart by multiple cellular mechanisms. A comparison with bone marrow progenitors, fibroblasts, and<br />
endothelial cells. Arterioscler Thromb Vasc Biol 2005; 25: 692-697<br />
• Latini R, Masson S, Anand I S, Missov E, Carlson M, Vago T, Angelici L, Barlera S, Parrinello G, Maggioni A P,<br />
Tognoni G, Cohn J N, Val-HeFT Investigators. Prognostic value of very low plasma concentrations of troponin T in<br />
patients with stable chronic heart failure. Circulation <strong>2007</strong>; 116: 1242-1249<br />
• Sarto P, Balducci E, Balconi G, Fiordaliso F, Merlo L, Tuzzato G, Pappagallo G L, Frigato N, Zanocco A, Forestieri C,<br />
Azzarello G, Mazzucco A, Valenti M T, Alborino F, Noventa D, Vinante O, Pascotto P, Sartore S, Dejana E, Latini R.<br />
Effects of exercise training on endothelial progenitor cells in patients with chronic heart failure. J Card Fail <strong>2007</strong>; 13:<br />
701-708.<br />
Maria Carla Roncaglioni si è laureata in Scienze Biologiche nel 1987 presso l’Università degli Stu<strong>di</strong> <strong>di</strong><br />
Milano.<br />
Attività formative<br />
1987 Laurea in Scienze Biologiche, Università <strong>di</strong> Milano<br />
1982-1983 Research Fellow presso il Dipartimento <strong>di</strong> Biochimica della Facoltà <strong>di</strong> Me<strong>di</strong>cina,<br />
Rijksuniversiteit of Limburg, Maastricht , Olanda (Prof. C. Hemker)<br />
1998-1999 Visiting Scientist presso la Car<strong>di</strong>ovascular Research Unit, dell’Hammersmith Hospital,<br />
London, UK (Prof. A. Maseri)<br />
Aree <strong>di</strong> interesse<br />
Coor<strong>di</strong>namento <strong>di</strong> trial clinici multicentrici e stu<strong>di</strong> osservazionali in <strong>di</strong>verse aree (neurologica,<br />
angiologica, car<strong>di</strong>ologica). Coor<strong>di</strong>namento <strong>di</strong> una rete <strong>di</strong> oltre 1000 Me<strong>di</strong>ci <strong>di</strong> Me<strong>di</strong>cina Generale<br />
attivamente coinvolti in progetti <strong>di</strong> ricerca epidemiologica e/o sperimentale nell’ambito della prevenzione<br />
delle malattie car<strong>di</strong>ovascolari.<br />
Ruoli attuali e passati in istituto<br />
dal 2001 Capo del Laboratorio <strong>di</strong> Ricerca in Me<strong>di</strong>cina Generale, <strong>Istituto</strong> <strong>di</strong> <strong>Ricerche</strong> <strong>Farmacologiche</strong><br />
“<strong>Mario</strong> Negri” <strong>di</strong> Milano<br />
dal 1989 Ricercatore Senior presso il Laboratorio <strong>di</strong> Farmacologia Clinica, <strong>Istituto</strong> <strong>di</strong> <strong>Ricerche</strong><br />
<strong>Farmacologiche</strong> “<strong>Mario</strong> Negri” <strong>di</strong> Milano<br />
dal 1974 Ricercatore presso il Laboratorio per lo Stu<strong>di</strong>o dell’Emostatsi e della Trombosi, <strong>Istituto</strong> <strong>di</strong><br />
<strong>Ricerche</strong> <strong>Farmacologiche</strong> “<strong>Mario</strong> Negri” <strong>di</strong> Milano<br />
Principali pubblicazioni<br />
• Avanzini F, Palumbo G, Alli C, Roncaglioni MC, Ronchi E, Cristofari M, Capra A, Rossi S, Nosotti L, Costantini C,<br />
Pietrofeso R, PPP - Primary Prevention Project. Effects of low-dose aspirin on clinic and ambulatory blood pressure in<br />
treated hypertensive patients. Am J Hypertens 2000; 13: 611-616<br />
• Tognoni G, Avanzini F, Pangrazzi J, Roncaglioni M C, Bertele V, de Gaetano G, Caimi V, Tombesi M, Colombo Fabio,<br />
Barlera S, PPP - Primary Prevention Project. Low-dose aspirin and vitamin E in people at car<strong>di</strong>ovascular risk: A<br />
randomized trial in general practice. Lancet 2001; 357: 89-95<br />
• Sacco M, Pellegrini F, Roncaglioni MC, Avanzini F, Tognoni G, Nicolucci A, PPP - Primary Prevention Project.<br />
Primary prevention of car<strong>di</strong>ovascular events with low-dose aspirin and vitamin E in type 2 <strong>di</strong>abetic patients. Results of<br />
the Primary Prevention Project (PPP) trial. Diabetes Care 2003; 26: 3264-3272<br />
• Roncaglioni MC, Avanzini F, Roccatagliata D, Monesi L, Tamayo-Benitez D, Tombesi M, Caimi V, Longoni P, Lauri<br />
D, Barlera S, Tognoni G, Collaborative Group Risk Prevention Study. How general practitioners perceive and grade the<br />
car<strong>di</strong>ovascular risk of their patients Eur J Car<strong>di</strong>ovasc Prev Rehabil 2004; 11: 233-238<br />
• Monesi L, Avanzini F, Barlera S, Caimi V, Lauri D, Longoni P, Roccatagliata D, Tombesi M, Tognoni G, Roncaglioni<br />
MC. Appropriate use of antiplatelets: is prescription in daily practice influenced by the global car<strong>di</strong>ovascular risk? Eur J<br />
Clin Pharmacol 2005; 61: 595-601<br />
116<br />
RAPPORTO ATTIVITA’ <strong>2007</strong>