Programma finale completo - SIF - Università degli Studi di Torino

115. Long-term treatment with CHF5074, a novel gamma-secretase modulator, markedly
reduces brain beta-amyloid in a transgenic mouse model of Alzheimer's disease
Imbimbo Bruno P. 1 , Del Giudice E. 2 , Miccichè F. 2 , Colavito D. 2 , D'Arrigo A. 2 , Dalle Carbonare
M. 2 , Villetti G. 1 , Facchinetti F. 1 , Volta R. 1 , Pietrini V., 3 Baroc M. F. 3 , Leon A. 2
1 Research & Development, Chiesi Farmaceutici, Via Palermo 26/A, 43100 Parma; 2 Research &
Innovation, Via Svizzera 16, 35127 Padua; 3 Department of Neurosciences, Neurology Section,
University of Parma, 43100 Parma
116. Angiogenesis in neurodegenerative processes: loss of regulatory A function
contributes to endothelial degeneration
Donnini Sandra, Cantara S., Giachetti A., Ziche M.
Pharmacology Section, Dept. Molecular Biology, University of Siena, Italy
117. The BH4 domain of Bcl-xl counteracts beta amyloid peptide toxicity on capillary
endothelium
Solito Raffaella, Donnini S., Cantara S., Giochetti A., Ziche M.
Section of Pharmacology, Department of Molecular Biology, University of Siena
118. Mitochondrial dysfunctions in a transgenic murine model of Alzheimer's disease
1 Cassano Tommaso, 2 Serviddio G., 2 Bellanti F., 2 Tamborra R., 1 Macheda T., 1 Morgese M.G.,
1 Trabace L., 3 Oddo S., 3 LaFerla F.M., 4 Cuomo V., 2 Vendemiale G.
1 Dept. of Biochemical Sciences Univ. of Foggia, Italy; 2 Dept. of Medical and Occupational
Sciences, Univ. of Foggia, Italy; 3 Dept. of Neurobiology and Behavior, Univ. of California,
Irvine, U.S.; 4 Dept. of Human Physiology and Pharmacology, Univ. of Rome “La Sapienza”,
Italy
119. Glia mediates neuroprotection by estrogen against ß-amyloid toxicity: effect
amplified by estrogen receptor overexpression
Carbonaro Viviana 1 , Frasca G. 1 , Merlo S. 1 , Caraci F. 2 , Copani A. 2 , Sortino M.A. 2
Departments of 1 Experimental and Clinical Pharmacology and 2 Pharmaceutical Sciences,
University of Catania
91
120. Cannabidiol in vivo suppresses A induced reactive gliosis
Scuderi Caterina 1,2 , Esposito G. 1 , Savani C. 1,4 , De Filippis D. 2 , Iuvone T. 2 , Steardo L. 1
1 Department of Human Physiology and Pharmacology “Vittorio Erspamer”, University of Rome
“La Sapienza” -
2 Department of Pharmacological Sciences, University of Palermo.
3 Department of Experimental Pharmacology, University of Naples Federico II. 4 Department of
Human Physiology and Pharmacology, University of Bari
121. In vivo characterization of DKK-1 expression in transgenic animal models of
Alzheimer's disease
Fiorentini Anna, Rosi M. C., Luccarini I., Grossi C., Casamenti F.
Department of Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy
122. in vivo effect of Clioquinol treatment in a mouse model of Alzheimer’s disease
Grossi Cristina, Rosi M. C., Fiorentini A., Luccarini I. , Casamenti F.
Department of Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy
123. Long-term treatment with a new anti-oligomeric beta-amyloid vaccine markedly
reduces brain beta-amyloid load in a transgenic mouse model of Alzheimer's disease
Imbimbo Bruno P. 1 , Pietrini V., 2 Baroc M.F. 2 , Del Giudice E. 3 , Miccichè F. 3 , Colavito D. 3 ,
D'Arrigo A. 3 , Dalle Carbonare M. 3 , Leon A. 3 , Villetti G. 1 , Facchinetti F. 1 , Moretto N. 4 , Ottonello
S. 4
1 Chiesi Farmaceutici, Via Palermo 26/A, Parma; 2 Department of Neurosciences, University of
Parma, Parma; 3 Research & Innovation, Via Svizzera 16, Padua; 4 Department of Biochemistry
and Molecular Biology, University of Parma, Viale G.P. Usberti 23/A, Parma
pag_dx.indd 1 30/05/2007 4.20.22