Programma finale completo - SIF - Università degli Studi di Torino
Programma finale completo - SIF - Università degli Studi di Torino
Programma finale completo - SIF - Università degli Studi di Torino
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115. Long-term treatment with CHF5074, a novel gamma-secretase modulator, markedly<br />
reduces brain beta-amyloid in a transgenic mouse model of Alzheimer's <strong>di</strong>sease<br />
Imbimbo Bruno P. 1 , Del Giu<strong>di</strong>ce E. 2 , Miccichè F. 2 , Colavito D. 2 , D'Arrigo A. 2 , Dalle Carbonare<br />
M. 2 , Villetti G. 1 , Facchinetti F. 1 , Volta R. 1 , Pietrini V., 3 Baroc M. F. 3 , Leon A. 2<br />
1 Research & Development, Chiesi Farmaceutici, Via Palermo 26/A, 43100 Parma; 2 Research &<br />
Innovation, Via Svizzera 16, 35127 Padua; 3 Department of Neurosciences, Neurology Section,<br />
University of Parma, 43100 Parma<br />
116. Angiogenesis in neurodegenerative processes: loss of regulatory A function<br />
contributes to endothelial degeneration<br />
Donnini Sandra, Cantara S., Giachetti A., Ziche M.<br />
Pharmacology Section, Dept. Molecular Biology, University of Siena, Italy<br />
117. The BH4 domain of Bcl-xl counteracts beta amyloid peptide toxicity on capillary<br />
endothelium<br />
Solito Raffaella, Donnini S., Cantara S., Giochetti A., Ziche M.<br />
Section of Pharmacology, Department of Molecular Biology, University of Siena<br />
118. Mitochondrial dysfunctions in a transgenic murine model of Alzheimer's <strong>di</strong>sease<br />
1 Cassano Tommaso, 2 Servid<strong>di</strong>o G., 2 Bellanti F., 2 Tamborra R., 1 Macheda T., 1 Morgese M.G.,<br />
1 Trabace L., 3 Oddo S., 3 LaFerla F.M., 4 Cuomo V., 2 Vendemiale G.<br />
1 Dept. of Biochemical Sciences Univ. of Foggia, Italy; 2 Dept. of Me<strong>di</strong>cal and Occupational<br />
Sciences, Univ. of Foggia, Italy; 3 Dept. of Neurobiology and Behavior, Univ. of California,<br />
Irvine, U.S.; 4 Dept. of Human Physiology and Pharmacology, Univ. of Rome “La Sapienza”,<br />
Italy<br />
119. Glia me<strong>di</strong>ates neuroprotection by estrogen against ß-amyloid toxicity: effect<br />
amplified by estrogen receptor overexpression<br />
Carbonaro Viviana 1 , Frasca G. 1 , Merlo S. 1 , Caraci F. 2 , Copani A. 2 , Sortino M.A. 2<br />
Departments of 1 Experimental and Clinical Pharmacology and 2 Pharmaceutical Sciences,<br />
University of Catania<br />
91<br />
120. Cannabi<strong>di</strong>ol in vivo suppresses A induced reactive gliosis<br />
Scuderi Caterina 1,2 , Esposito G. 1 , Savani C. 1,4 , De Filippis D. 2 , Iuvone T. 2 , Steardo L. 1<br />
1 Department of Human Physiology and Pharmacology “Vittorio Erspamer”, University of Rome<br />
“La Sapienza” -<br />
2 Department of Pharmacological Sciences, University of Palermo.<br />
3 Department of Experimental Pharmacology, University of Naples Federico II. 4 Department of<br />
Human Physiology and Pharmacology, University of Bari<br />
121. In vivo characterization of DKK-1 expression in transgenic animal models of<br />
Alzheimer's <strong>di</strong>sease<br />
Fiorentini Anna, Rosi M. C., Luccarini I., Grossi C., Casamenti F.<br />
Department of Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy<br />
122. in vivo effect of Clioquinol treatment in a mouse model of Alzheimer’s <strong>di</strong>sease<br />
Grossi Cristina, Rosi M. C., Fiorentini A., Luccarini I. , Casamenti F.<br />
Department of Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy<br />
123. Long-term treatment with a new anti-oligomeric beta-amyloid vaccine markedly<br />
reduces brain beta-amyloid load in a transgenic mouse model of Alzheimer's <strong>di</strong>sease<br />
Imbimbo Bruno P. 1 , Pietrini V., 2 Baroc M.F. 2 , Del Giu<strong>di</strong>ce E. 3 , Miccichè F. 3 , Colavito D. 3 ,<br />
D'Arrigo A. 3 , Dalle Carbonare M. 3 , Leon A. 3 , Villetti G. 1 , Facchinetti F. 1 , Moretto N. 4 , Ottonello<br />
S. 4<br />
1 Chiesi Farmaceutici, Via Palermo 26/A, Parma; 2 Department of Neurosciences, University of<br />
Parma, Parma; 3 Research & Innovation, Via Svizzera 16, Padua; 4 Department of Biochemistry<br />
and Molecular Biology, University of Parma, Viale G.P. Usberti 23/A, Parma<br />
pag_dx.indd 1 30/05/2007 4.20.22