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Programma finale completo - SIF - Università degli Studi di Torino

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109. The nitric oxide-leleasing derivative of furbiprofen HCT1026 decreases vulnerability<br />

of nigrostriatal dopaminergic neurons to MPTP via a switch of glia proinflammatory<br />

phenotype: implications for treatment of Parkinson's <strong>di</strong>sease<br />

L’Episcopo Francesca 1 , Testa N. 1 , Caniglia S. 1 , Tirolo C. 1 , Giaquinta G. 1 , Arcieri P. 1 , Serra<br />

P.A. 2 , Bazzu G. 2 , Morale M. C. 1 , Impagnatiello F. 3 , Marchetti B. 1,2<br />

1 Neuropharmacology, OASI Institute Researc and Care (IRCCS) Troina (EN), Italy and<br />

2 Department of Pharmacology, University of Sassari, Me<strong>di</strong>cal School, Sassari, Italy, and<br />

3 Nicox Research Institute, Bresso, Milano, Italy<br />

110. Neuroinflammatory response in the acute MPTP rodent model of Parkinson's<br />

<strong>di</strong>sease: time-dependent correlation with histopathological, neurochemical and<br />

behavioral response to nigrostriatal injury and repair<br />

L’Episcopo Francesca 1 , Salani G. 2 , Serra P.A. 3 , Caniglia S. 1 , Tirolo C. 1 ,Giaquinta G. 1 , Testa<br />

N. 1 , Rocchitta G. 3 , Calia G. 3 , Manca A. 3 , Morale M.C. 1 , Pluchino S. 2 , Martino G. 3 , Marchetti<br />

B. 1,2<br />

1 Neuropharmacology, OASI Institute for Research and Care (IRCCS) Troina (EN), Italy<br />

2 Neuroimmunology Unit, Department of Neurology and Physiology, San Raffaele Scientific<br />

Institute, Milano, and 3 Dept. Pharmacology, University of Sassari Me<strong>di</strong>cal School, Sassari,<br />

Italy<br />

90<br />

111. S100B protein promoted tau protein hyperphosphorilation through DKK-1 protein<br />

up-regulation and relative WNT pathway <strong>di</strong>sruption in cultured human neurons<br />

Esposito Giuseppe 1 , Scuderi C. 1, 4 , De Filippis D. 2 , Iuvone T. 2 , Savani C. 1, 5 , Lu Jie 3 , Sheen<br />

Volney 3 , Steardo L. 1<br />

1 Department of Human Physiology and Pharmacology “Vittorio Erspamer”, University of Rome<br />

“La Sapienza” - 2 Department of Experimental Pharmacology, University of Naples Federico<br />

II.<br />

3 Department of Neurology, Beth Israel Deaconess Me<strong>di</strong>cal Center, Harvard Me<strong>di</strong>cal School,<br />

Boston<br />

4 Department of Pharmacological Sciences, University of Palermo. 5 Department of Human<br />

Physiology and Pharmacology, University of Bari<br />

112. Amyloid Precursor Protein and Presenilin1 Interact with the Adaptor Grb2 and<br />

Modulate ERK1,2 Signaling<br />

Clau<strong>di</strong>o Russo 5 , Nizzari M., Venezia V. 1 , Repetto E. 1 , Corsi V. 2 , Magrassi R. 2 , Gagliani M.C. 3 ,<br />

Florio T. 1 , Schettini G. 1 , Tacchetti C. 3 , Russo T. 4 , Diaspro A. 2<br />

1 Dip. Oncologia, Biologia e Genetica, Università <strong>di</strong> Genova, 2 Dip. Fisica, Università <strong>di</strong> Genova,<br />

3 Dip.Me<strong>di</strong>cina Sperimentale, Università <strong>di</strong> Genova, 4 Dip.Biochimica, Università <strong>di</strong> Napoli<br />

Federico II, 5 Dip. Scienze per la Salute, Università del Molise<br />

113. Nitric oxyde and dopaminergic system: neurochemical interactions in -amyloid<br />

injected rats<br />

Schiavone Stefania (a) , Lanni C. (b) , Cuomo V. (c) , Trabace L. (a) , Govoni S. (b)<br />

(a) Dept. Biome<strong>di</strong>cal Sciences, University of Foggia, Foggia, Italy; (b) Dept. of Experimental<br />

and Applied Pharmacology, University of Pavia, Pavia, Italy; (c) Dept. of Human Physiology<br />

and Pharmacology, Vittorio Espamer, University of Rome La Sapienza, Rome, Italy<br />

114. Alterations of tau protein and effect of lithium salts treatment on TgCRND8 mice<br />

Rosi Maria Cristina, Grossi C., Fiorentini A., Luccarini I., Casamenti F.<br />

Department of Pharmacology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy<br />

pag_sx.indd 1 30/05/2007 4.18.41

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