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0-TESTO COMPLETO.pdf - Fondazione Santa Lucia

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Sezione III: Attività per progetti<br />

cious and specific treatment of patients who will develop the different types of<br />

dementia.<br />

This project will also suggest the potential role of cognitive rehabilitation<br />

therapy and caregivers support on the cognitive and behavioural symptom<br />

progression of MCI.<br />

To obtain this result potentially means a reduced cost of the management<br />

of dementia for the national health service and a better outcome of the illness<br />

for patients.<br />

OUTPUT(S) OF THE PROJECT<br />

An improvement in the capability to predict the clinical evolution of the<br />

classic subtypes of MCI through their reclassification is expected, keeping in<br />

mind the behavioural and social parameters that have never been considered<br />

before for diagnostic purposes. In this way the MCI-dementia conversion<br />

could be predicted with greater specificity for each subtype of neurodegenerative<br />

dementia. The clinical evolution of the sample treated with cognitive<br />

rehabilitation could indicate if a controlled scientific trial would be useful.<br />

These outputs will be reached at the end of the 18-months follow-up period.<br />

New cognitive rehabilitation strategies for patients with MCI will be<br />

developed by using a set of specifically devised memory and attention computerized<br />

tasks. This will permit to extend the cognitive rehabilitation intervention<br />

outside the hospital, allowing the availability of a more extensive and<br />

less expensive rehabilitative training for patients at risk of dementia. The<br />

development of new cognitive rehabilitation protocols will be obtained within<br />

the first 6 months of the project. Results on the effectiveness of the cognitive<br />

rehabilitation therapy on the MCI-dementia conversion rate will be achieved<br />

at the end of the follow-up period.<br />

Finally, the feasibility and effectiveness of a support program for MCI<br />

caregivers will be obtained. The program will provide caregivers active<br />

involvement through knowledge, emotions and problems sharing and<br />

resources enhancement giving rise to a support network in which technique<br />

and humanization might contribute to delay illness progression. The output<br />

of this strategy regarding the MCI-dementia conversion rate will be reached at<br />

the end of the project.<br />

MILESTONES ALONGSIDE THE PROJECT<br />

1. To build a network among all the participating units in order to permit<br />

a correct flow of communication.<br />

2. To train all the professionals participating in the projects to administer<br />

the rating scales and to measure the inter-rater reliability.<br />

3. To enrol all 100 MCI patients as defined by the project program.<br />

4. To sub-classify the MCI subtypes on the basis of the defined criteria.<br />

5. To measure the validity of the new sub-classification of the MCI subtypes<br />

on the basis of the behavioural markers.<br />

720 2009

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