0-TESTO COMPLETO.pdf - Fondazione Santa Lucia

Sezione III: Attività per progetti
immediate neighboring research environments. Finally, we hope our results
will stimulate development of novel drugs to two disorders that lack satisfactory
treatment. This will provide the ultimate added value to those afflicted by
the diseases and be financially rewarding for the countries involved.
SUBPROJECTS
1. CALCIUM HOMEOSTASIS DYSFUNCTION AND MITOCHONDRIAL DAMAGE
IN ALZHEIMER’S AND HUNTINGTON’S DISEASES
Responsabile scientifico: Fabrizio Tagliavini – Fondazione IRCCS Istituto
Neurologico Carlo Besta Neuropatologia – Neurologia 5 – Italy
2. SYNAPTIC DYSFUNCTION AND NEURODEGENERATION: ROLE OF DREAM
MUTANTS
Responsabile scientifico: Jose R. Naranjo – CSIC Centro Nacional de
Biotecnología, Mol Cell Biol – Spain
3. UNDERSTANDING EARLY ALTERATIONS IN SYNAPTIC AND AXONAL DYSFUNCTION
AND SEEKING FOR NOVEL TARGETS FOR THERAPEUTIC INTERVENTION
IN NEURODEGENERATIVE DISEASES
Responsabile scientifico: Jia-Yi Li – Lund University, Department of
Experimental Medical Science – Sweden
4. ALTERATIONS IN PROTEIN RECYCLING AND SYNAPTIC DEGENERATION
IN HUNTINGTON’S DISEASE
Responsabile scientifico: Pierluigi Nicotera – Leicester University, MRC
Toxicology Unit – United Kingdom
5. THE ROLE OF EXOSOMES IN THE TRAFFICKING OF PROTEINS ASSOCIATED
WITH ALZHEIMER DISEASE
Responsabile scientifico: Giuliano Binetti – IRCCS Centro S.Giovanni di
Dio-Fatebenefratelli, NeuroBioGen Lab-Memory Clinic – Italy
Segue la descrizione del sottoprogetto 1 all’interno del quale, al
punto 2.3, è riportato lo specifico contributo dell’Unità Operativa 2 che
fa capo alla Fondazione Santa Lucia.
612 2009