samwvera nervis nevralgiis mkurnaloba: karbamazepini ... - GPC
samwvera nervis nevralgiis mkurnaloba: karbamazepini ... - GPC
samwvera nervis nevralgiis mkurnaloba: karbamazepini ... - GPC
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aseve SesaZlebelia izolirebulad ganviTardes fsiqikuri simptomebi rogoricaa:<br />
halucinaciebi, depresiuli mdgomareobebi, agresiuli qceva, azrovnebiTi procesebis<br />
Seferxeba, daqveiTebuli iniciativa, faruli fsiqozis aqtivacia.<br />
agreTve aRwerilia xanSiSesul paciebtebSi an cerebraluri dazianebebis dros<br />
SemTxvevebi, rodesac viTardeba pirisa da saxis uneblie moZraobebi, kunTovani<br />
diskineziuri moSlilobani.<br />
ofTalmologiuri simptomebi: izolirebuli koniuqitviti, mxedvelobis gardamavali<br />
moSliloba. glaukomis dros TvalSida wneva periodulad aucileblad unda<br />
gakontroldes.<br />
saWmlis momnelebeli sistema: mkurnalobis sawyis etapze SesaZlebelia ganviTardes:<br />
umadoba, piris simSrale, gulisreva, Rebineba, diarea an yabzoba. aRwerilia muclis<br />
tkivilis, piris Rrusa da xaxis anTebis (stomatiti, glositi, gingivitis)<br />
calkeuli SemTxvevebi. aRniSnuli simptomebi spontanurad qreba mkurnalobis<br />
dasrulebidan an dozis Semcirebidan 8-14 dRis Semdeg.<br />
aRniSnuli fenomenis Tavidan acileba SesaZlebelia mkurnalobis TandaTanobiT<br />
dawyebiT, progresulad mzardi dozebis miRebiT.<br />
zogjer adgili aqvs RviZlis testebis cvlielebebs, iSviaTad viTardeba hepatitis,<br />
sxvadasxva formis SedarebiT izolirebuli RviZlis qsovilis anTebiTi procesebi<br />
(qolestaturi, hepatocelularuli, granulomatozuri da Sereuli hepatitebi,<br />
pankeatitebi).<br />
gulsisxlZarRvTa sistema: ganskauTrebiT xanSiSesul pacientebSi, an gulis<br />
ukmarisobis dros, iSviaTad SeiZleba ganviTardes: bradikardia, riTmis darRvevebi,<br />
iSemiuri kardiopaTiis gauareseba. calkeul SemTxvevebSi - gulis doneze<br />
gamtareblobis darRvevebi (atrio-ventrikuluri blokada cnobierebis dakargviT),<br />
arteriuli wnevis momateba an daqveiTeba. arteriuli wnevis daqveiTeba aRiniSneba<br />
gansakuTrebiT im SemTxvevaSi Tu <strong>karbamazepini</strong>s maRali dozebi gamoiyeneba.<br />
sasunTqi sistema: respiratoruli hipermgrZnobelobis niSnebi – cxeleba, dispnoe,<br />
filtvebSi Segubeba, filtvis fibrozi.<br />
Zvlovan-kunTovani sistema: iSviaTad viTardeba saxsrebisa da kunTebis tkivili<br />
(arTralgia, mialgia), kunTovani krunCxvebi.<br />
metabolizmi: antidiurezuli moqmedebis gamo karbamazepinma SeiZleba gamoiwvios<br />
hiponatriemia RebinebiT, Tavis tkiviliT da dezorientaciiT. iSviaT SemTxvevebSi<br />
viTardeba SeSupeba da wonis momateba. ukiduresad iSviaTad viTardeba ginekomastia<br />
da galaqtorea. aseve dafiqsirebulia plazmaSi kacliumis donis daqveiTebis<br />
SemTxvevebi.<br />
Sard-sasqeso sistema: iSviaTad aRiniSneba proteinuria, hematuria, oliguria, rac<br />
preparatis antidiurezuli moqmedebiT ganpirobebuli Tirkmlis ukmarisobis<br />
gamovlinebaa, agreTve SesaZlebelia ganviTardes dizuria, polakiuria, rac<br />
Sesabamisad TirkmlebSi Sardis Seferxebis gamovlinebaa.<br />
calkeul SemTxvevebSi - seqsualuri darRvevebi, rogoricaa libidos daqveiTeba da<br />
impotencia.<br />
gansakuTrebuli gafrTxilebani<br />
gansakuTrebuli yuradReba unda mieqcies kanis alergiul reaqciebs, hematologiur<br />
da hepatotoqsiur reaqciebs. mkurnalobis xangrZlivi kursis SemTxvevaSi imisaTvis,<br />
rom aRniSnuli darRvevebi ganisazRvros adreul stadiaze, rekomendirebulia<br />
periodulad Catardes saTanado laboratoriuli gamokvlevebi - sisxlisa da<br />
RviZlis funqcionaluri mdgomareobis dasadgenad. agreTve aucilebelia<br />
<strong>karbamazepini</strong>s da sxva antiepileptiuri medikamantebis sisxlSi donis perioduli<br />
gansazRvra kombinirebuli mkurnalobis SemTxvevaSi. sisxlis saerTo analizi da
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