samwvera nervis nevralgiis mkurnaloba: karbamazepini ... - GPC
samwvera nervis nevralgiis mkurnaloba: karbamazepini ... - GPC
samwvera nervis nevralgiis mkurnaloba: karbamazepini ... - GPC
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alprozolami, klonmazepami, klozapini, doqsiciklini, etosuqcimidi, galoperidoli,<br />
hormonaluri kontraceptivebi, fenitoini.<br />
liTiumTan erTdroulma gamoyenebam SesaZloa gamoiwvios nevrologiuri gverdiTi<br />
efeqtebis gamovlinebis riskis gazrda.<br />
karbamazepinma SesaZloa gamoiwvios kontraceptivebis usafrTxoebis daqveiTeba.<br />
<strong>karbamazepini</strong> aqveiTebs alkoholis mimarT pacientTa tolerantobas. mkurnalobis<br />
periodSi ar aris rekomendirebuli alkoholis miReba.<br />
orsuloba da laqtacia<br />
orsulobis dros <strong>karbamazepini</strong>s gamoyeneba ukiduresad sariskoa, vinaidan igi iwvevs<br />
nayofis dazianebas. epidemiologiuri kvlevebiT dadginda, rom orsulobis dros<br />
<strong>karbamazepini</strong>s gamoyenebis Sedegad viTardeba nayofis Tandayolili anomaliebi– maT<br />
Soris spina bifida. aqedan gamomdinare <strong>karbamazepini</strong>s daniSvna orsulebSi<br />
(gansakuTrebiT pirvel trimestrSi) rekomendirebuli mxolod im SemTxvevaSi TuU<br />
potenciuri Terapiuli sargebeli awonasworebs preparatis nayofis mimarT zianis<br />
miyenebis risks. im SemTxvevaSo Tu miRebulia gadawyvetileba orsulobis periodSi<br />
misi daniSvnis Sesaxeb, mkacrad rekomendirebulia misi daniSvna monoTerapiis saxiT.<br />
laqtaciis periodSi <strong>karbamazepini</strong>s gamoyeneba unda Sewydes, vinaidan igi<br />
eqskretirdeba dedis rZeSi.<br />
avtomobilis marTva da teqnikur xelsawyoebTan muSaoba<br />
pacientebi, romelTac aReniSnebaT <strong>karbamazepini</strong>s gamoyenebis periodSi Zilianoba da<br />
Tavbrusxveva, unda gafrTxilebuli iyvenen imis Sesaxeb rom arsebobs riski<br />
avtomobilis marTvisa da teqnikur mowyobilobebTan muSaobis dros, agreTve iseTi<br />
saqmianobis dros, romelic moiTxovs yuradRebis koncentrirebasa da normaluri<br />
refleqsebis arsebobas.<br />
gverdiTi efeqtebi<br />
gverdiTi movlenebis ganviTareba damokidebulia preparatis dozaze. gverdiTi<br />
efeqtebis ganviTrebis sixSire metia mkurnalobis dasawyisSi da kombinirebuli<br />
mkurnalobis dros.<br />
dozisa da mkurnalobis meTodis mkacrad dacvis SemTxvevaSi medikamenti maRali<br />
tolerantobiT xasiaTdeba.<br />
yvelaze xSirad gverdiTi efeqtebi vlindeba mkurnalobis sawyis fazaSi, esenia:<br />
Tavbrusxveva, Zilianoba, barbaci, gulisreva, Rebineba.<br />
sisxlmbadi sistema: aplastiuri anemia, agrnaulocitozi, pancitopenia, Zvlis tvinis<br />
daTrgunva, leikopenia, eozinofilia, porfiria.<br />
kanis reaqciebi: gamonayari, urtikaria, toqsiuri epidermuli nekrolizi (Lyell’s<br />
sindromi), stivens-jonsonis sindromi, kanis pigmentaciis cvlileba, eqsfoliatiuri<br />
dermatiti, multiformuli da kvanZovani eriTema, purpura, ganvrcobili lupus<br />
eriTematozis gauareseba. iSviaTad alopecia, oflianoba.<br />
centraluri nevruli sistema: sedacia, Zilianoba, cnobierebis darRvevebi,<br />
Tavbrusxveva, siarulisa da moZraobis moSlilobani (cerebraluri ataqsia).<br />
zogierT SemTxvevaSi vlindeba Tavis tkivili. xanSiSesul pacientebSi SeiZleba<br />
gaviTardes SfoTva da dezorientacia. iSviaTad uneblie moZraobebi (nistagmi) da<br />
calkeul SemTxvevebSi ki metyvelebis, mgrZnoblobis moSlilobani, aseve kunTovani<br />
asTenia, <strong>nervis</strong> anTeba (periferiuli nevriti), rogorc qveda kidurebis paralizis<br />
gamovlineba (paresTeziebi). agreTve iSviaT SemTxvevebSi aRiricxeba mxedvelobis<br />
dabindva, mxedvelobiTi halucianaciebi.
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