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Sistemi transdermici e sviluppi

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Ibuprofen amount permeated mg/cm (<br />

2 )<br />

120<br />

100<br />

Scelta della matrice<br />

80<br />

60<br />

40<br />

20<br />

Ruolo della matrice nell’assorbimento<br />

0<br />

0 4 8 12 16 20 24<br />

Time (h)<br />

Polyaminomethacrylate<br />

Poly(acrylatevinylacetate)<br />

P.Minghetti, et al., Acta Technologiae et Legis Medicamenti, XII, 3: 199-212, 2001. .<br />

Ibuprofen release amount<br />

100<br />

90<br />

80<br />

70<br />

60<br />

50<br />

40<br />

Form. 1<br />

Form. 2<br />

0 4 8<br />

tempo (ore)

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