<strong>Progetto</strong> LaSER. Lotta <strong>alla</strong> <strong>sepsi</strong> <strong>in</strong> <strong>Emilia</strong>-<strong>Romagna</strong> • Paul M., Silbiger I., Groz<strong>in</strong>sky S., Soares-Weiser K., Leibovici L. Beta lactam antibiotic monotherapy versus beta lactam-am<strong>in</strong>oglycoside antibiotic comb<strong>in</strong>ation therapy for <strong>sepsi</strong>s. Cochrane Database Syst Rev, 1): CD003344-, 25 Jan 2006. Review. PMID: 16437452 • Petrucci N., Iacovelli W. Ventilation with lower tidal volumes versus traditional tidal volumes <strong>in</strong> adults for acute lung <strong>in</strong>jury and acute respiratory distress syndrome. Cochrane Database Syst Rev, 2): CD003844-, 2004a. Review • Rhodes A., Bennett E.D. Early goal-directed therapy: an evidence-based review. Crit Care Med, 32 (11 Suppl): S448-S450, Nov 2004. Review. PMID: 15542954 [PubMed - <strong>in</strong>dexed for MEDLINE] • Rivers E., Nguyen B., Havstad S., Ressler J., Muzz<strong>in</strong> A., Knoblich B., Peterson E., Tomlanovich M. Early goal-directed therapy <strong>in</strong> the treatment of severe <strong>sepsi</strong>s and septic shock. N Engl J Med, 345 (19): 1368-1377, 8 Nov 2001. • Russell J.A. Management of <strong>sepsi</strong>s. N Engl J Med, 355 (16): 1699-1713, 19 Oct 2006. • Shapiro N.I., Howell M.D., Talmor D., Lahey D., Ngo L., Buras J., Wolfe R.E., Weiss J.W., Lisbon A. Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol. Crit Care Med, 34 (4): 1025-1032, Apr 2006. PMID: 16484890 [PubMed - <strong>in</strong>dexed for MEDLINE] • Ste<strong>in</strong>berg K.P., Hudson L.D., Goodman R.B., Hough C.L., Lanken P.N., Hyzy R., Thompson B.T., Ancukiewicz M., National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Cl<strong>in</strong>ical Trials Network. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med, 354 (16): 1671-1684, 20 Apr 2006. PMID: 16625008 [PubMed - <strong>in</strong>dexed for MEDLINE] • The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung <strong>in</strong>jury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med, 342 (18): 1301-1308, 4 May 2000. • Uzzan B., Cohen R., Nicolas P., Cucherat M., Perret G.Y. Procalciton<strong>in</strong> as a diagnostic test for <strong>sepsi</strong>s <strong>in</strong> critically ill adults and after surgery or trauma: a systematic review and meta-analysis. Crit Care Med, 34 (7): 1996-2003, 2006. • van den Berghe G., Wouters P., Weekers F., Verwaest C., Bruyn<strong>in</strong>ckx F., Schetz M., Vlasselaers D., Ferd<strong>in</strong>ande P., Lauwers P., Bouillon R. Intensive <strong>in</strong>sul<strong>in</strong> therapy <strong>in</strong> the critically ill patients. N Engl J Med, 345 (19): 1359-1367, 8 Nov 2001. • van den Berghe G., Wilmer A., Hermans G., Meersseman W., Wouters P.J., Milants I., Van Wijngaerden E., Bobbaers H., Bouillon R. Intensive <strong>in</strong>sul<strong>in</strong> therapy <strong>in</strong> the medical ICU. N Engl J Med, 354 (5): 449-461, 2 Feb 2006. • van Gestel A., Bakker J., Veraart C.P., van Hout B.A. Prevalence and <strong>in</strong>cidence of severe <strong>sepsi</strong>s <strong>in</strong> Dutch <strong>in</strong>tensive care units. Crit Care, 8 (4): R153-R162, 2004. Dossier 143 104
<strong>Progetto</strong> LaSER. Lotta <strong>alla</strong> <strong>sepsi</strong> <strong>in</strong> <strong>Emilia</strong>-<strong>Romagna</strong> • Villar J., Kacmarek R.M., Perez-Mendez L., Aguirre-Jaime A. A high positive end- expiratory pressure, low tidal volume ventilatory strategy improves outcome <strong>in</strong> persistent acute respiratory distress syndrome: a randomized, controlled trial. Crit Care Med, 34 (5): 1311-1318, May 2006. • V<strong>in</strong>cent J.L., Bernard G.R., Beale R., Doig C., Putensen C., Dha<strong>in</strong>aut J.F., Artigas A., Fumagalli R., Macias W., Wright T., Wong K., Sund<strong>in</strong> D.P., Turlo M.A., Janes J. Drotrecog<strong>in</strong> alfa (activated) treatment <strong>in</strong> severe <strong>sepsi</strong>s from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment. Crit Care Med, 33 (10): 2266-2277, 2005. • V<strong>in</strong>cent J.L., Gerlach H. Fluid resuscitation <strong>in</strong> severe <strong>sepsi</strong>s and septic shock: an evidence-based review. Crit Care Med, 32 (11 Suppl): S451-S454, 2004. • Vriesendorp T.M., van Santen S., DeVries J.H., De Jonge E., Rosendaal F.R., Schultz M.J., Hoekstra J.B. Predispos<strong>in</strong>g factors for hypoglycemia <strong>in</strong> the <strong>in</strong>tensive care unit. Crit Care Med, 34 (1): 96-101, Jan 2006. PMID: 16374162 [PubMed - <strong>in</strong>dexed for MEDLINE] • WHO. Drotrecog<strong>in</strong> alfa: not <strong>in</strong>dicated for paediatric <strong>sepsi</strong>s. WHO Drug Information, 19 (2): 112-113, 2005. Dossier 143 105
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