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Septic shock-A shock A melting pot of shock etiologies Dellinger RP. Crit <strong>Care</strong> Med 2003;31:946-956
SEPSI E IRA Rilascio citochine,attivazione monocitaria e adesione leucociti Disfunzione endoteliale Riduzione della volemia “efficace efficace” volemia e perdita della autoregulazione nel rene Alterazione nel rapporto flusso ematico intrarenale/flusso ematico totale e riduzione del rilascio di O2 nella parte spessa dell’ansa dell ansa ascendente Ipoperfusione e ipossia nalla parte esterna della midollare Quando inizia lo Shock Settico …. . Inizia anche l’IRA! l IRA!
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CORSO AVANZATO PER MEDICI Trattamen
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→ Il flusso ematico renale rappre
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Factors that render the kidney susc
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IRA: definizione L’IRA IRA è una
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Incidenza dell’IRA dell IRA (Vinc
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August 28-30, 28 30, 2000 New York
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ORIGINAL INVESTIGATIONS The Outcome
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Hospital Mortality Rate in RRT Pati
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• IRA,frequente complicanza in IC
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DIAGNOSES IN 544 PATIENTS WITH ARF
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Acute Renal Failure in critically i
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M.E. Ostermann, D. Taube, C.J. Morg
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A higher level of knowledge needs t
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Vivino G, Antonelli M, Moro ML, Cot
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Risk factors increased by • Age
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Agents and Events That Ameliorate o
Page 34 and 35: Drugs Associated with Acute Renal F
Page 36 and 37: RI=0.63 Renal Protection through st
Page 38 and 39: A.de Mendonça, J.L. Vincent, P.M.
Page 40 and 41: • Infection … they concluded th
Page 42 and 43: De Mendonça A et al. Acute renal f
Page 44 and 45: • Advanced age • Altered previo
Page 46 and 47: Quale forma di IRA è frequentement
Page 48 and 49: Sepsi: Stadi e definizioni Infezion
Page 50 and 51: Arterial Vasodilatation and Renal V
Page 52 and 53: Effect of Membrane Potential on the
Page 54 and 55: good and bad effects of nitric oxid
Page 56 and 57: FORMATION OF LPS/PROTEIN COMPLEXES
Page 58 and 59: Tubular-Cell Injury and Repair in I
Page 60 and 61: ACTIVATION OF HUMORAL PATHWAY L P S
Page 62 and 63: A disorder due to incontrolled infl
Page 64 and 65: The pathogenesis of septic acute re
Page 66 and 67: Jo e colleghi hanno recentemente di
Page 68 and 69: APOPTOSIS
Page 70 and 71: Acute renal failure Norbert Lameire
Page 73: 600 500 400 300 200 100 0 PaO2/FiO2
Page 77 and 78: ml/die 8000 7000 6000 5000 4000 300
Page 79 and 80: mg/dL 700 600 500 400 300 200 100 0
Page 81 and 82: Lasciato a se stesso e non contrast
Page 83: Strategie di protezione
Page 87 and 88: Renal Perfusion Pressure: Pressure
Page 89 and 90: • Riempimento volemico per manten
Page 91 and 92: Acute phase: Patients who have dila
Page 93 and 94: Cardiovascular changes associated w
Page 95 and 96: Dellinger RP. Crit Care Med 2003;31
Page 97 and 98: Edema removal by a dialysis techniq
Page 100: “independent independent from an
Page 103 and 104: …..guardando gli effetti biologic
Page 105 and 106: APOPTOSIS IN SEPSIS PHVHF decreased
Page 107 and 108: Terapia anti apoptosica? The Acute
Page 109 and 110: (%) Survival Rate of Early Vs Late
Page 112 and 113: EARLY ISOVOLEMIC HAEMOFILTRATION IN
Page 114 and 115: - Trattamento extracorporeo del san
Page 116 and 117: MOST Brain Liver mRNA/NfKb Cytokine
Page 118 and 119: Early detection of ARF,especially i
Page 120 and 121: . . Grazie per l’attenzione l att
Page 122 and 123: The Response to Pathogens, Involvin
Page 125 and 126: Immunologic Response of Three Hypot
Page 127 and 128: Dal momento che la sepsi è un proc
Page 129: IMMUNOMODULAZIONE : Il goal della M
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