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ACTIVATION OF HUMORAL PATHWAY L P S ANAPHYLATOXINS (C3a - C5a) Hageman F XII Endothelium PLATELET AGGREGATION Vasc. Vasc. Resistance Vasc. Vasc. Permeability NEUTROPHIL ACTIVATION
Sepsi: Perdita dell'omeostasi Mediatori proinfiammatori Lesione endoteliale Espressione del fattore tessutale Produzione di trombina + Coagulazione Coagulazione + Infiammazione Infiammazione Omeostasi - Fibrinolisi Fibrinolisi Aumento di PAl-1 Aumento di TAFI a Riduzione della Proteina C (La Proteina C attivata endogena inibisce PAI-1) PAI-1= inibitore di tipo 1 del’attivatore del plasminogeno;TAFI a = inibitore della fibrinolisi attivabile dalla trombina. Carvalho and Freeman. J Crit Illness. 1994;9:51; Kidokoro e coll. Shock. 1996;5:223; Vervloet e coll. Semin Thromb Hemost. 1998;24:33.
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CORSO AVANZATO PER MEDICI Trattamen
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→ Il flusso ematico renale rappre
Page 6 and 7:
Factors that render the kidney susc
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IRA: definizione L’IRA IRA è una
Page 10 and 11: Incidenza dell’IRA dell IRA (Vinc
Page 12 and 13: August 28-30, 28 30, 2000 New York
Page 14 and 15: ORIGINAL INVESTIGATIONS The Outcome
Page 16 and 17: Hospital Mortality Rate in RRT Pati
Page 18 and 19: • IRA,frequente complicanza in IC
Page 20 and 21: DIAGNOSES IN 544 PATIENTS WITH ARF
Page 22 and 23: Acute Renal Failure in critically i
Page 24 and 25: M.E. Ostermann, D. Taube, C.J. Morg
Page 26 and 27: A higher level of knowledge needs t
Page 28 and 29: Vivino G, Antonelli M, Moro ML, Cot
Page 30 and 31: Risk factors increased by • Age
Page 32 and 33: Agents and Events That Ameliorate o
Page 34 and 35: Drugs Associated with Acute Renal F
Page 36 and 37: RI=0.63 Renal Protection through st
Page 38 and 39: A.de Mendonça, J.L. Vincent, P.M.
Page 40 and 41: • Infection … they concluded th
Page 42 and 43: De Mendonça A et al. Acute renal f
Page 44 and 45: • Advanced age • Altered previo
Page 46 and 47: Quale forma di IRA è frequentement
Page 48 and 49: Sepsi: Stadi e definizioni Infezion
Page 50 and 51: Arterial Vasodilatation and Renal V
Page 52 and 53: Effect of Membrane Potential on the
Page 54 and 55: good and bad effects of nitric oxid
Page 56 and 57: FORMATION OF LPS/PROTEIN COMPLEXES
Page 58 and 59: Tubular-Cell Injury and Repair in I
Page 62 and 63: A disorder due to incontrolled infl
Page 64 and 65: The pathogenesis of septic acute re
Page 66 and 67: Jo e colleghi hanno recentemente di
Page 68 and 69: APOPTOSIS
Page 70 and 71: Acute renal failure Norbert Lameire
Page 73: 600 500 400 300 200 100 0 PaO2/FiO2
Page 77 and 78: ml/die 8000 7000 6000 5000 4000 300
Page 79 and 80: mg/dL 700 600 500 400 300 200 100 0
Page 81 and 82: Lasciato a se stesso e non contrast
Page 83 and 84: Strategie di protezione
Page 85 and 86: SEPSI E IRA Rilascio citochine,atti
Page 87 and 88: Renal Perfusion Pressure: Pressure
Page 89 and 90: • Riempimento volemico per manten
Page 91 and 92: Acute phase: Patients who have dila
Page 93 and 94: Cardiovascular changes associated w
Page 95 and 96: Dellinger RP. Crit Care Med 2003;31
Page 97 and 98: Edema removal by a dialysis techniq
Page 100: “independent independent from an
Page 103 and 104: …..guardando gli effetti biologic
Page 105 and 106: APOPTOSIS IN SEPSIS PHVHF decreased
Page 107 and 108: Terapia anti apoptosica? The Acute
Page 109 and 110: (%) Survival Rate of Early Vs Late
Page 112 and 113:
EARLY ISOVOLEMIC HAEMOFILTRATION IN
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- Trattamento extracorporeo del san
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MOST Brain Liver mRNA/NfKb Cytokine
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Early detection of ARF,especially i
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. . Grazie per l’attenzione l att
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The Response to Pathogens, Involvin
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Immunologic Response of Three Hypot
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Dal momento che la sepsi è un proc
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IMMUNOMODULAZIONE : Il goal della M
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