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ORIGINAL INVESTIGATIONS The Outcome of Acute Renal Failure in the Intensive Care Unit According to RIFLE: Model Application, Sensitivity and Predictability Nihal Y. Abosaif, MD, Yasser A. Tolba, FRCA, FCA-RCSI, Mike Heap, FRCA, Jean Russell, MScStat, and A. Meguid El Nahas, PhDAm J Kidney Dis 46:1038-1048.© 2005 Conclusion: RIFLE classification can improve the ability of such older and established ICU scoring systems as APACHE II and SAPS II in predicting outcome of ICU patients with ARF
L’IRA è correlata ad elevata mortalità ? • Chertow GM et al. Prognostic stratification in critically ill patients with acute renal failure requiring dialysis. Arch Intern Med 155: 1505-1511,1995 (70%) • Brivet FG et al. The French Study Group on acute renal failure: acute renal failure in intensive care units-causes, outcome,and prognosis factors of hospital mortality:a prospective multicenter study. Crit Care Med 24:192- 198,1996 (53%) • Metnitz PG et al.Effect of acute renal failure requiring renal replacement on outcome in critically ill patients. Crit Care Med 30: 2051- 2058,2002 (15% vs 52%)
Page 1 and 2: CORSO AVANZATO PER MEDICI Trattamen
Page 3: → Il flusso ematico renale rappre
Page 6 and 7: Factors that render the kidney susc
Page 8 and 9: IRA: definizione L’IRA IRA è una
Page 10 and 11: Incidenza dell’IRA dell IRA (Vinc
Page 12 and 13: August 28-30, 28 30, 2000 New York
Page 16 and 17: Hospital Mortality Rate in RRT Pati
Page 18 and 19: • IRA,frequente complicanza in IC
Page 20 and 21: DIAGNOSES IN 544 PATIENTS WITH ARF
Page 22 and 23: Acute Renal Failure in critically i
Page 24 and 25: M.E. Ostermann, D. Taube, C.J. Morg
Page 26 and 27: A higher level of knowledge needs t
Page 28 and 29: Vivino G, Antonelli M, Moro ML, Cot
Page 30 and 31: Risk factors increased by • Age
Page 32 and 33: Agents and Events That Ameliorate o
Page 34 and 35: Drugs Associated with Acute Renal F
Page 36 and 37: RI=0.63 Renal Protection through st
Page 38 and 39: A.de Mendonça, J.L. Vincent, P.M.
Page 40 and 41: • Infection … they concluded th
Page 42 and 43: De Mendonça A et al. Acute renal f
Page 44 and 45: • Advanced age • Altered previo
Page 46 and 47: Quale forma di IRA è frequentement
Page 48 and 49: Sepsi: Stadi e definizioni Infezion
Page 50 and 51: Arterial Vasodilatation and Renal V
Page 52 and 53: Effect of Membrane Potential on the
Page 54 and 55: good and bad effects of nitric oxid
Page 56 and 57: FORMATION OF LPS/PROTEIN COMPLEXES
Page 58 and 59: Tubular-Cell Injury and Repair in I
Page 60 and 61: ACTIVATION OF HUMORAL PATHWAY L P S
Page 62 and 63: A disorder due to incontrolled infl
Page 64 and 65:
The pathogenesis of septic acute re
Page 66 and 67:
Jo e colleghi hanno recentemente di
Page 68 and 69:
APOPTOSIS
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Acute renal failure Norbert Lameire
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600 500 400 300 200 100 0 PaO2/FiO2
Page 77 and 78:
ml/die 8000 7000 6000 5000 4000 300
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mg/dL 700 600 500 400 300 200 100 0
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Lasciato a se stesso e non contrast
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Strategie di protezione
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SEPSI E IRA Rilascio citochine,atti
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Renal Perfusion Pressure: Pressure
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• Riempimento volemico per manten
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Acute phase: Patients who have dila
Page 93 and 94:
Cardiovascular changes associated w
Page 95 and 96:
Dellinger RP. Crit Care Med 2003;31
Page 97 and 98:
Edema removal by a dialysis techniq
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“independent independent from an
Page 103 and 104:
…..guardando gli effetti biologic
Page 105 and 106:
APOPTOSIS IN SEPSIS PHVHF decreased
Page 107 and 108:
Terapia anti apoptosica? The Acute
Page 109 and 110:
(%) Survival Rate of Early Vs Late
Page 112 and 113:
EARLY ISOVOLEMIC HAEMOFILTRATION IN
Page 114 and 115:
- Trattamento extracorporeo del san
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MOST Brain Liver mRNA/NfKb Cytokine
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Early detection of ARF,especially i
Page 120 and 121:
. . Grazie per l’attenzione l att
Page 122 and 123:
The Response to Pathogens, Involvin
Page 125 and 126:
Immunologic Response of Three Hypot
Page 127 and 128:
Dal momento che la sepsi è un proc
Page 129:
IMMUNOMODULAZIONE : Il goal della M
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