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- Trattamento extracorporeo del sangue - • L’idea che il sangue possa essere detossificato in pazienti con sepsi non è nuova Stein et al. Intens <strong>Care</strong> Med 1990 Grootendorst et al. Intens <strong>Care</strong> Med 1992 La depurazione di microorganismi o dei loro prodotti dal circolo potrebbe essere un approccio logico in corso di sepsi. Tuttavia, nella maggioranza dei casi quando si fa diagnosi di sepsi non è più presente batteremia (viremia, fungemia) e nemmeno sono rilevabili i loro prodotti in circolo (es. endotossine) Struttura dell’LPS LPS Tetta et al. Ther Apher 2002 Struttura dell
..the .. the future may see CRRT move beyond its initial goal of providing renal support to the area of immune modulation in sepsis and SIRS…. SIRS . Bellomo-Ronco Bellomo Ronco
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CORSO AVANZATO PER MEDICI Trattamen
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→ Il flusso ematico renale rappre
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Factors that render the kidney susc
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IRA: definizione L’IRA IRA è una
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Incidenza dell’IRA dell IRA (Vinc
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August 28-30, 28 30, 2000 New York
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ORIGINAL INVESTIGATIONS The Outcome
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Hospital Mortality Rate in RRT Pati
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• IRA,frequente complicanza in IC
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DIAGNOSES IN 544 PATIENTS WITH ARF
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Acute Renal Failure in critically i
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M.E. Ostermann, D. Taube, C.J. Morg
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A higher level of knowledge needs t
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Vivino G, Antonelli M, Moro ML, Cot
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Risk factors increased by • Age
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Agents and Events That Ameliorate o
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Drugs Associated with Acute Renal F
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RI=0.63 Renal Protection through st
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A.de Mendonça, J.L. Vincent, P.M.
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• Infection … they concluded th
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De Mendonça A et al. Acute renal f
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• Advanced age • Altered previo
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Quale forma di IRA è frequentement
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Sepsi: Stadi e definizioni Infezion
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Arterial Vasodilatation and Renal V
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Effect of Membrane Potential on the
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good and bad effects of nitric oxid
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FORMATION OF LPS/PROTEIN COMPLEXES
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Tubular-Cell Injury and Repair in I
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ACTIVATION OF HUMORAL PATHWAY L P S
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A disorder due to incontrolled infl
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Page 66 and 67: Jo e colleghi hanno recentemente di
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Page 70 and 71: Acute renal failure Norbert Lameire
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Page 81 and 82: Lasciato a se stesso e non contrast
Page 83 and 84: Strategie di protezione
Page 85 and 86: SEPSI E IRA Rilascio citochine,atti
Page 87 and 88: Renal Perfusion Pressure: Pressure
Page 89 and 90: • Riempimento volemico per manten
Page 91 and 92: Acute phase: Patients who have dila
Page 93 and 94: Cardiovascular changes associated w
Page 95 and 96: Dellinger RP. Crit Care Med 2003;31
Page 97 and 98: Edema removal by a dialysis techniq
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Page 103 and 104: …..guardando gli effetti biologic
Page 105 and 106: APOPTOSIS IN SEPSIS PHVHF decreased
Page 107 and 108: Terapia anti apoptosica? The Acute
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Page 118 and 119: Early detection of ARF,especially i
Page 120 and 121: . . Grazie per l’attenzione l att
Page 122 and 123: The Response to Pathogens, Involvin
Page 125 and 126: Immunologic Response of Three Hypot
Page 127 and 128: Dal momento che la sepsi è un proc
Page 129: IMMUNOMODULAZIONE : Il goal della M
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