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Atti delle Giornate di Coniglicoltura AsIC 2011 – 8-9 aprile 2011 – Forlì – Italia Viudes-de-castro, m.P.; García-Ximénez, F.; Vicente, J.s., 1995. embryo recovery from eliminating does of three selected rabbit strains for an embryo bank. investigación agraria: Prod. san. anim. 145-152. Viudes-de-castro, m.P., Lavara, r., marco-Jimenez, F., Cortell, C., Vicente, J.s., 2007. ovulation induced by mucosa vaginal absorption of buserelin and triptorelin in rabbit. Theriogenology 68:1031-1036. walton, a., hammond, J., 1928. observations on ovulation in the rabbit. br. J. exp. biol. 6:190-198. Karten, m.J., rivier, J.e., 1986. Gonadotropin-relasing hormon analog design. structure-function studies towards the development of agonists and antagonists: rationale and perspective. endocrinol. rev. 7:44-56. Zanagnolo, V., dharmarajan, a.m., hesla, J., Wallach, e.e., 1996. effects of a gonadotropin-releasing hormone analog on rabbit ovarian function. endocrinology 137:5400-5406. Zapletal, d., Pavlik, a., 2008. The effect of lecirelin (Gnrh) dosage on the reproductive performance of nulliparous and lactating rabbit does. anim. repr. sci. 104: 306–315. 40
Relazioni su invito FAcTORS AFFEcTINg EFFIcAcy OF INTRAVAgINAL AdmINISTRA- TION OF gnRh ANALOgUES FOR OVULATION INdUcTION IN RAbbIT dOES reboLLar P.G. Department of Animal Production, Polytechnic University, Madrid, spain Pilar García Rebollar, Departamento de Producción Animal, Escuela Técnica superior de Ingenieros Agrónomos, Universidad Politécnica de Madrid, Ciudad Universitaria s/n 28040 Madrid, spain - Tel. +34 91 4524868 - Fax: +34 91 5499763 *Corresponding author: pilar.grebollar@upm.es AbSTRAcT The vagina, unlike other mucoses, is very dynamic with respect to its histology and physiology. This leads to the existence of a long list of factors included in the vaginal environment that affect substances absorption deposited there. recently, it has been obtained normal ovulation rates in rabbit does inseminated which were induced with an intravaginal dose of Gnrh analogue. This text provides a review with information about the structure, tissues, secretions, contractions, and innervations of vagina of rabbit which can affect their absorption profile. Key words: GnRH, Absorption, Vagina, Rabbit. INTROdUcTION rabbit is an animal model useful for studying sperm distribution and function in the female. it is known the site of semen deposition with natural mating or artificial insemination, the seminal characteristics, the anatomy of the rabbit doe genital tract and the environment of the lumen. The most important interest in reproductive rabbit does has been limited to ovary, oviducts and uterine horns. The vagina has been only considered to be a part of the birth canal. however, the vagina is self-evidently involved in the sexual function. The new possibilities to include analogues of Gnrh in the seminal doses are opening new pathways to study the absorption capacity of this reproductive channel. gROSS ANATOmy ANd VAgINAL bARRIER The reproductive tract of the rabbit doe is bipartite from the ovary to the vagina. The vagina of new Zealand does is about 14-19 cm long. The urethral orifice opens into the vagina about 6 cm proximal from the introitus (Wingerd, 1984). immediate- 41
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