(.pdf) dr.ssa Antonella Ferro - Progettoeventi
(.pdf) dr.ssa Antonella Ferro - Progettoeventi
(.pdf) dr.ssa Antonella Ferro - Progettoeventi
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
T-DM1: the first-in-class HER2-targeted<br />
antibody-<strong>dr</strong>ug conjugate<br />
Target expression: HER2<br />
Monoclonal antibody: trastuzumab<br />
Cytotoxic agent: DM1<br />
Highly potent chemotherapy<br />
(maytansine derivative)<br />
Linker<br />
Systemically stable<br />
Breaks down in target cancer cell<br />
T-DM1