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(.pdf) dr.ssa Antonella Ferro - Progettoeventi

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Neoadjuvant Trastuzumab significantly<br />

pCR<br />

(%)<br />

improves pCR rates in the NOAH trial<br />

90<br />

80<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

Without Trastuzumab<br />

With Trastuzumab<br />

p=0.002<br />

HER2 positive<br />

(n=228)<br />

p=0.004<br />

23 43 17 19 55 29<br />

HER2<br />

negative<br />

(n=99)<br />

HER2 positive<br />

(n=62)<br />

Total population IBC population<br />

pCR, pathological complete response in the breast<br />

IBC, inflammatory breast cancer<br />

HER2<br />

negative<br />

(n=14)<br />

Baselga et al 2007; Gianni et al 2007

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