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(.pdf) dr.ssa Antonella Ferro - Progettoeventi

(.pdf) dr.ssa Antonella Ferro - Progettoeventi

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Potenziale meccanismo di trastuzumab in<br />

base a clinical setting<br />

Clinical setting Inhibition of ADCC Inhibition of<br />

proliferation DNA repair<br />

Survival Recist Recist<br />

Neoadjuvant<br />

-trastuzumab alone + ++ -<br />

-trastuzumab plus<br />

chemotherapy + +/- ++<br />

Adjuvant<br />

-concomitant + +/- ++<br />

-sequential ++ +/- -<br />

Molecular Targeting Unit

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