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Respiratori
Percorsi Assistenziali Neonatologici Anno 2008
Due
72
10
10 ppm iNO per 4 ore
Responders Non Responders
Ridurre iNO a 5 ppm Aumentare iNO fino a 20 ppm
Responders Non Responders
Continuare con 5 ppm per 20 ore
(max 72 ore) Stop iNO
7
FiO 2 < 0,50
Ridurre iNO fino a 1 ppm
Stop iNO
Neonato con EG < 34
settimane con OI > 15
1. Konduri GG. New approaches for persistent pulmkonary hypertension of newborn. Clin Perinatol 2004;31:591-611.
2. Finer NN, Barrington KJ. Nitric oxide for respiratory failure in infants born at or near term. Cochrane Database Syst Rev
2006;4:CD000399.
3. Ballard RA, Truog WE, Cnaan A et al. Inhaled nitric oxide in preterm infants undergoing mechanical ventilation. N Engl J
Med2006;355:343-353.
4. Kinsella JP, Cutter GR, Walsh WF et al. Early inhaled nitric oxide therapy in premature infants with respiratory failure. N Engl J Med
2006;355:354-364