Special topic: Metagenomics - Genome Sciences
Special topic: Metagenomics - Genome Sciences
Special topic: Metagenomics - Genome Sciences
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“Its nice to have a few trillion friends”<br />
Gut microbiome holds ≈100 trillion bacterial cells; that is 10x more bacterial cells than<br />
human cells<br />
Composite metagenome of this microbiome contains 100x more genes than our human<br />
genome:<br />
‣ Perform transformations: synthesis of essential vitamins, and metabolism of drugs &<br />
xenobiotics.<br />
‣ Affects susceptibility to pathogens and diseases.<br />
‣ Human Gut Microbiome Initiative: The next human genome project.<br />
Helicobacter pylori:<br />
Gastritis<br />
Helicobacter<br />
hepaticus:<br />
Inflammatory bowel<br />
disease<br />
What are these 2.5M<br />
genes doing in our<br />
bodies?
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