Special topic: Metagenomics - Genome Sciences

grouping shows that our current GOS sampling methodology
will not cover all protein families, and perhaps misses some
protein families Rate that are of exclusive protein to higher discovery eukaryotes. The
large section of clusters that include all three groupings
uences Are Added
e y-axis denotes the number of clusters (in thousands). Seven datasets with increasing
d in the text. The blue curve shows the number of core sets of size 3 for the seven
own. Linear regression gives slopes 0.027 (R 2 ¼ 0.999), 0.011 (R 2 ¼ 0.999), 0.0053 (R 2 ¼
nd size 20, respectively.
only sequenc
members of k
clustering pa
detected by a
Figure 2. Rate of Discovery of Clusters as (Nonredundant) Sequences Are Added
The x-axis denotes the number of sequences (in millions) and the y-axis denotes the number
numbers of (nonredundant) sequences are chosen as described in the text. The blue curve
datasets. Curves for core set sizes 5, 10, and 20 are also shown. Linear regression gives
0.999), and 0.0024 (R 2 0437
March 2007 | Volume 5 | Issue 3 | e16
¼ 0.996) for size 3, size 5, size 10, and size Yooseph 20, et respectively. al., 2007