teori sediaan-terkunci

Kerosene
Cetyl alcohol
Stearyl alcohol
Carbon tetrachloride
Lauric acid
Oleic acid
Stearic acid
12-14
13-16
15-16
16
16
17
17
-
-
-
-
-
-
-
Martin, 1993, hal. 490:
In general, o/w emulsion are formed when the HLB of emulsifier is within the range about 9
to 12, and w/o emulsions are formed when the range is about 3 to 6.
RPS, 21 st ed., hal. 760-761:
HLB value
1-3
7-10
13-20
13-15
8-16
3-8
Function
Antifoaming agent
Wetting agent
Solubilizers
Detergent
o/w emulsion
w/o emulsion
Nilai HLB beberapa emulgator: (Modul Praktikum Farmasi Fisika, hlm. 53-54)
Emulgator
HLB
Parsial ester asam lemak dari sorbitan:
Sorbitan mono laurat (Span 20) 8,6
Sorbitan mono palmitat (Span 40) 6,7
Sorbitan mono stearat (Span 60) 4,7
Sorbitan tri stearat (Span 65) 2,1
Sorbitan mono oleat (Span 80) 4,3
Sorbitan tri oleat (Span 85) 1,8
Parsial ester asam lemak dari polioksi etilensorbitan:
Polioksietilen sorbitan (20) mono laurat (Tween 20) 16,7
Polioksietilen sorbitan (4) mono laurat (Tween 21) 13,3
Polioksietilen sorbitan (20) mono palmitat (Tween 40) 15,6
Polioksietilen sorbitan (20) mono stearat (Tween 60) 14,9
Polioksietilen sorbitan (4) mono oleat (Tween 61) 9,6
Polioksietilen sorbitan tri stearat (Tween 65) 10,5