lotegra (desloratadini) Semadgenloba: garsiT dafaruli erTi tableti ...
lotegra (desloratadini) Semadgenloba: garsiT dafaruli erTi tableti ...
lotegra (desloratadini) Semadgenloba: garsiT dafaruli erTi tableti ...
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<strong>lotegra</strong>(<strong>desloratadini</strong>)<strong>Semadgenloba</strong>:<strong>garsiT</strong> <strong>dafaruli</strong> <strong>erTi</strong> <strong>tableti</strong> Seicavs:aqtiuri nivTiereba: <strong>desloratadini</strong> – 5 mg.damxmare nivTierebebi: laqtoza, magniumis oqsidi, mikrokristaluri celuloza, polieTilenglikoli,Jelatinizirebuli saxamebeli, titanis dioqsidi, TuTiis stearatiFD & C Blue #2 aluminium lake, hipromeloza,4000 CR.aTq kodi: R06AX27.farmakoTerapiuli jgufi:antihistaminuri preparatebi sistemuri gamoyenebisaTvis.H1-histaminuri receptorebis blokatori.farmakodinamika:<strong>lotegra</strong>s gaaCnia antihistaminuri, antialergiuli da anTebis sawinaaR-mdego moqmedeba.igi warmoadgens H1- histaminuri receptorebis blokators, romelic ar avlens sedaciur moqmedebas.peroraluri miRebisas <strong>desloratadini</strong> (loratadinis pirveladi aqtiuri metaboliti)avlens periferiuli histaminuri H1-receptorebis SerCeviT blokirebas. igi Trgunavs citostatikurreaqciaTa kaskads: anTebis sawinaaRmdego citokinebis gamoyofas, maT Soris interleikin-4-is, interleikin-6-is, interleikin-8-is, interleikin-13-is, RANTES tipisanTebis sawinaaRmdego hemokinebis gamoyofas, aseve Trgunavs superoqsiduri anionebis produqciasaqtivirebuli polimorfulbirTvuli neirofilebiT, Trgunavs eozinofilebisadgeziasa da hemotaqsiss, adgeziis molekulaTa eqspresias, maT Soris R-seleqtinis, lgESualeduri histaminisda D2 prostaglandinisa da C4 leikotrienis gamoyofas.farmakokinetika:preparats axasiaTebs kargi absorbcia kuW-nawlavis traqtidan. plazmaSi maqsimaluri koncentracia miiRwevadaaxloebiT 3 saaTSi. naxevargamoy-ofis periodi daaxloebiT 27 saaTs Seadgens. bioSeRwevadoba miRebulidozis proporciulia (dozis diapazoni meryeobs 5 mg-dan20 mg-mde). igi ar gadis hematoencefalur bariers da praqtikulad ar metabolizdeba RviZlSi. aRwevsplacentarul bariers da gadadis dedis rZeSi.gamoyenebis Cveneba:- sezonuri polinozi da qronikuli alergiuli riniti- alergiuli koniunqtiviti (ceminebis, cxviridan gamonadenis, cxviris dacobis da qavilis, cremldenis,Tvalebis qavilis da hiperemiis moxsnis an Semsubuqebis mizniT)- qaviliT mimdinare dermatozebi- qronikuli idiopaTuri WinWris cieba (kanis qavilis da gamonayaris Semcirebisa da gaqrobis mizniT)dozirebis reJimi:<strong>lotegra</strong> iniSneba peroralurad 5 mg erTxel dReSi, kvebisgan damoukideblad. <strong>tableti</strong> gadaylapeT mTlianad,dauReWavad, daayoleT wyali.gverdiTi movlenebi:SesaZloa Tavis tkivili.iSviaTad piris simSrale, sisuste.ukuCveneba:orsuloba, laqtacia, momatebuli mgrZnobeloba <strong>desloratadini</strong>s mimarT.urTierTqmedeba sxva samkurnalo saSualebebTan:kvlevam aCvena, rom <strong>desloratadini</strong>s ketokonazolTan da eriTromicinTan erTad miReba klinikuradmniSvnelovan cvlilebebs ar iwvevs.sakvebTan erTad miReba organizmSi <strong>desloratadini</strong>s ganawilebaze gavlenas ar axdens.<strong>desloratadini</strong> ar aZlierebs alkoholis moqmedebas centralur nervul sistemaze.gansakuTrebuli miTiTeba:preparati sifrTxiliT gamoiyeneba Tirkmlis ukmarobis mwvave formis dros.gamoyeneba pediatriaSi:SesaZlebelia eqimis daniSnulebis Sesabamisad.avtomobilisa da sxva meqanizmebis marTvis unarze gavlena.<strong>desloratadini</strong> ar moqmedebs avtomobilis marTvisa da iseT samuSaoTa Sesrulebis unarze, romelicmoiTxovs swraf fsiqomotorul reaqcias.gamoSvebis forma:<strong>tableti</strong> 5 mg, SefuTvaSi <strong>garsiT</strong> <strong>dafaruli</strong> 10 <strong>tableti</strong> blisterze.1 blisteri gamoyenebis instruqciasTan erTad moTavsebulia muyaos kolofSi.Senaxvis pirobebi:SeinaxeT bavSvebisaTvis miuwvdomel adgilas, 25 0 C-mde temperaturis pirobebSi.vargisianobis vada :preparatis vargisianobis vadaa 2 weli warmoebis TariRidan.ar gamoiyenoT vargisobis vadis gasvlis Semdeg.afTiaqidan gacemis piroba:farmacevtuli produqtis jgufi III (gaicema receptis gareSe).
mwarmoebeli:`farmasaians~. ink (kanada)misamarTi: 6111, roialmaunTsuitis aveniu, monreali, kvebeki H4P 2T4.kanadawarmoebulia:ss ji-pi-si-s dakveTiTmisamarTi: 0108, sanapiros q #6. Tbilisi, saqarTve
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