Publications de nos chercheursrépertoriées par axe de rechercheBIOLOGIE INTÉGRATIVE DESSYSTÈMES ET CHIMIE MÉDICINALE1. Audet, N., Galés, C., Archer-Lahlou, É., Vallières, M.,Schiller, P.W., Bouvier, M., Pineyro, G."Bioluminescence resonance energy transferassays reveal ligand-specific conformationalchanges within preformed signaling complexescontaining δ-opioid receptors and heterotrimeric Gproteins". Journal of Biological Chemistry,283(22): 15078-15088, <strong>2008</strong>.2. Ballet, S., Misicka, A., Kosson, P., Lemieux, C., Chung,N.N., Schiller, P.W., Lipkowski, A.W., Tourwé, D."Blood-brain barrier penetration by twodermorphin tetrapeptide analogues: Role oflipophilicity vs structural flexibility". Journal ofMedicinal Chemistry, 51(8): 2571-2574, <strong>2008</strong>.3. Coulombe, B., Blanchette, M., Jeronimo, C. "Stepstowards a repertoire of comprehensive maps ofhuman protein interaction networks: the HumanProteotheque Initiative (HuPI)". Biochemistryand cell biology = Biochimie et biologiecellulaire, 86(2): 149-156, <strong>2008</strong>.4. Di Lello, P., Miller Jenkins, L.M., Mas, C., Langlois, C.,Malitskaya, E., Fradet-Turcotte, A., Archambault,J., Legault, P., Omichinski, J.G. "p53 and TFIIEαshare a common binding site on the Tfb1/p62subunit of TFIIH". Proceedings of the NationalAcademy of Sciences of the United States ofAmerica, 105(1): 106-111, <strong>2008</strong>.5. Domecq, C.V., Trinh, V., Langelier, M.F., Archambault,J., Coulombe, B. "Inhibitors of multisubunit RNApolymerases as tools to study transcriptionalmechanisms in prokaryotes and eukaryotes ".Current Chemical Biology, 2(1): 20-31, <strong>2008</strong>.6. Fichna, J., do-Rego, J.-C., Chung, N.N., Costentin, J.,Schiller, P.W., Janecka, A. "[Dmt 1 , D-1-Nal 3 ]morphiceptin, a novel opioid peptide analogwith high analgesic activity". Pepti<strong>des</strong>, 29(4):633-638, <strong>2008</strong>.7. Fichna, J., do-Rego, J.-C., Janecki, T., Staniszewska,R., Poels, J., Broeck, J.V., Costentin, J., Schiller,P.W., Janecka, A. "Novel highly potent μ-opioidreceptor antagonist based on endomorphin-2structure". Bioorganic and Medicinal ChemistryLetters, 18(4): 1350-1353, <strong>2008</strong>.opioid peptide derived antagonists containing(2S)-2-Methyl-3-(2,6-dimethyl-4-carbamoylphenyl)propanoic acid [(2S)-Mdcp]".Journal of Medicinal Chemistry, 51(18): 5866-5870, <strong>2008</strong>.9. Harada, R., Vadnais, C., Sansregret, L., Leduy, L.,Bérubé, G., Robert, F., Nepveu, A. "Genomewidelocation analysis and expression studiesreveal a role for p110 CUX1 in the activation ofDNA replication genes". Nucleic AcidsResearch, 36(1): 189-202, <strong>2008</strong>.10. Krueger, B.J., Jeronimo, C., Roy, B.B., Bouchard, A.,Barrandon, C., Byers, S.A., Searcey, C.E.,Cooper, J.J., Bensaude, O., Cohen, É.A.,Coulombe, B., Price, D.H. "LARP7 is a stablecomponent of the 7SK snRNP while P-TEFb,HEXIM1 and hnRNP A1 are reversiblyassociated". Nucleic Acids Research, 36(7):2219-2229, <strong>2008</strong>.11. Moody, C.A., Fradet-Turcotte, A., Archambault, J.,Laimins, L.A. "Human papillomaviruses activatecaspases upon epithelial differentiation to induceviral genome amplification". Proceedings of theNational Academy of Sciences of the UnitedStates of America, 104(49): 19541-19546, <strong>2007</strong>.12. Parat, M., McNicoll, N., Wilkes, B., Fournier, A., DeLéan, A. "Role of extracellular domaindimerization in agonist-induced activation ofnatriuretic peptide receptor A". MolecularPharmacology, 73(2): 431-440, <strong>2008</strong>.13. Truscott, M., Harada, R., Vadnais, C., Robert, F.,Nepveu, A. "p110 CUX1 cooperates with E2Ftranscription factors in the transcriptionalactivation of cell cycle-regulated genes".Molecular and Cellular Biology, 28(10): 3127-3138, <strong>2008</strong>.14. Zieleniak, A., Rodziewicz-Motowidlo, S., Rusak, L.,Chung, N.N., Czaplewski, C., Witkowska, E.,Schiller, P.W., Ciarkowski, J., Izdebski, J."Deltorphin analogs restricted via a urea bridge:Structure and opioid activity". Journal of PeptideScience, 14(7): 830-837, <strong>2008</strong>.15. Znaidi, S., Weber, S., Al-Abdin, O.Z., Bomme, P.,Saidane, S., Drouin, S., Lemieux, S., De Deken,X., Robert, F., Raymond, M. "Genomewidelocation analysis of Candida albicans Upc2p, aregulator of sterol metabolism and azole drugresistance". Eukaryotic Cell, 7(5): 836-847,<strong>2008</strong>.8. Ghosh, A., Luo, J., Liu, C., Weltrowska, G., Lemieux,C., Chung, N.N., Lu, Y., Schiller, P.W. "Novel47
CANCER1. Bijl, J., Krosl, J., Lebert-Ghali, C.-E., Vacher, J.,Mayotte, N., Sauvageau, G. "Evidence for Hoxand E2A-PBX1 collaboration in mouse T-cellleukemia". Oncogene, <strong>2008</strong>.2. Cadieux, C., Harada, R., Paquet, M., Côté, O., Trudel,M., Nepveu, A., Bouchard, M. "Polycystic kidneyscaused by sustained expression of CUX1 isoformp75". Journal of Biological Chemistry, 283(20):13817-13824, <strong>2008</strong>.Journal of Immunology, 37(12): 3551-3563,<strong>2007</strong>.10. Pata, M., Heraud, C., Vacher, J. "OSTM1 bone defectreveals an intercellular hematopoietic crosstalk".Journal of Biological Chemistry, <strong>2008</strong>.11. Szuber, N., Buss, J.L., Soe-Lin, S., Felfly, H., Trudel,M., Ponka, P. "Alternative treatment paradigm forthalassemia using iron chelators". ExperimentalHematology, 36(7): 773-785, <strong>2008</strong>.3. Heyd, F., Carmo-Fonseca, M., Möröy, T. "Differentialisoform expression and interaction with the P32regulatory protein controls the subcellularlocalization of the splicing factor U2AF26".Journal of Biological Chemistry, 283(28):19636-19645, <strong>2008</strong>.4. Kirjavainen, A., Sulg, M., Heyd, F., Alitalo, K., Ylä-Herttuala, S., Möröy, T., Petrova, T.V., Pirvola, U."Prox1 interacts with Atoh1 and Gfi1, andregulates cellular differentiation in the inner earsensory epithelia". Developmental Biology,<strong>2008</strong>.5. Komander, D., Patel, M., Laurin, M., Fradet, N.,Pelletier, A., Barford, D., Côté, J.-F. "An alphahelicalextension of the ELMO1 pleckstrinhomology domain mediates direct interaction toDOCK180 and is critical in Rac signaling".Molecular Biology of the Cell, <strong>2008</strong>.6. Maranda, B., Chabot, G., Décarie, J.-C., Pata, M.,Azeddine, B., Moreau, A., Vacher, J. "Clinical andcellular manifestations of OSTM1-related infantileosteopetrosis". Journal of Bone and MineralResearch, 23(2): 296-300, <strong>2008</strong>.7. Möröy, T., Zeng, H., Jin, J., Schmid, K.W., Carpinteiro,A., Gulbins, E. "The zinc finger protein andtranscriptional repressor Gfi1 as a regulator of theinnate immune response". Immunobiology,213(3-4): 341-352, <strong>2008</strong>.8. Otero, J.E., Dai, S., Foglia, D., Alhawagri, M., Vacher,J., Pasparakis, M., Abu-Amer, Y. "Defectiveosteoclastogenesis by IKKbeta -null precursors isa result of RANKL-induced JNK-dependentapoptosis and impaired differentiation". Journalof Biological Chemistry, 283(36): 24546-24553,<strong>2008</strong>.9. Pargmann, D., Yücel, R., Kosan, C., Saba, I., Klein-Hitpass, L., Schimmer, S., Heyd, F., Dittmer, U.,Möröy, T. "Differential impact of thetranscriptional repressor Gfi1 on mature CD4(+)and CD8(+) T lymphocyte function". EuropeanIMMUNITÉ ET INFECTIONS VIRALES1. Binette, J., Dube, M., Mercier, J., Cohen, E.A."Requirements for the selective degradation ofCD4 receptor molecules by the humanimmunodeficiency virus type 1 Vpu protein in theendoplasmic reticulum". Retrovirology, 4(1): 75,<strong>2007</strong>.2. Di Noia, J.M., Williams, G.T., Chan, D.T.Y.,Buerstedde, J.-M., Baldwin, G.S., Neuberger,M.S. "Dependence of antibody genediversification on uracil excision". Journal ofExperimental Medicine, 204(13): 3209-3219,<strong>2007</strong>.3. Veillette, A., Dong, Z., Latour, S. "Consequence of theSLAM-SAP signaling pathway in innate-like andconventional lymphocytes". Immunity, 27(5): 698-710, <strong>2007</strong>.4. Westerman, K.A., Ao, Z., Cohen, E.A., Leboulch, P."Design of a trans protease lentiviral packagingsystem that produces high titer virus".Retrovirology, 4(1): 96, <strong>2007</strong>.5. Belanger, S., Tai, L.-H., Anderson, S.K., Makrigiannis,A.P. "Ly49 cluster sequence analysis in a mousemodel of diabetes: An expanded repertoire ofactivating receptors in the NOD genome". Genesand Immunity, 9(6): 509-512, <strong>2008</strong>.6. Carlyle, J.R., Mesci, A., Fine, J.H., Chen, P., Bélanger,S., Tai, L.-H., Makrigiannis, A.P. "Evolution ofthe Ly49 and Nkrp1 recognition systems".Seminars in Immunology, <strong>2008</strong>.7. Colina, R., Costa-Mattioli, M., Dowling, R.J.O.,Jaramillo, M., Tai, L.-H., Breitbach, C.J.,Martineau, Y., Larsson, O., Rong, L., Svitkin,Y.V., Makrigiannis, A.P., Bell, J.C., Sonenberg,N. "Translational control of the innate immuneresponse through IRF-7". Nature, 452(7185):323-328, <strong>2008</strong>.48
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