Anemia Management Protocol: CKD Non-Dialysis - BC Renal Agency

ESA DOSING INTERVAL ADJUSTMENT TABLESUPDATED APRIL 2012FOR CKD NON-DIALYSIS PATIENTSDarbepoetin (Aranesp ® ) Dosing Interval Adjustment Table(to use up current supplies at home)CURRENT DOSE10 mcg every 2 weeks20 mcg every 2 weeks30 mcg every 2 weeks40 mcg every 2 weeks50 mcg every 2 weeks60 mcg every 2 weeks80 mcg every 2 weeks100 mcg every 2 weeks130 mcg every 2 weeks150 mcg every 2 weeks100 mcg every 1 weekINCREASED DOSECHANGE INTERVAL TOEvery 10 daysCheck with MDDECREASED DOSECHANGE INTERVAL TOHoldEvery 21 DaysEvery 10 daysEpoetin alpha (Eprex ® ) Dosing Interval Adjustment Table(to use up current supplies at home)CURRENT DOSE1000 units every 1 week2000 units every 1 week3000 units every 1 week4000 units every 1 week5000 units every 1 week6000 units every 1 week8000 units every 1 week10,000 units every 1 week6000 units twice per week8000 units twice per week10,000 units twice per weekINCREASED DOSECHANGE INTERVAL TOEvery 5 daysEvery 3 daysCheck with MDDECREASED DOSECHANGE INTERVAL TOHoldEvery 10 daysEvery 5 days