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Thursday, May 29 >>> morning<br />
Motor neuron diseases<br />
8.30 am-10.00 am Plenary lectures XAuditorium<br />
Chairperson > Mimoun Azzouz<br />
8.30 am-9.15 am Vincent Meininger, France<br />
> Biomarkers and clinical trials in amyotrophic lateral sclerosis<br />
9.15 am-10.00 am Judith Melki, Israel<br />
> Genetics and mo<strong>de</strong>l systems in upper and lower motor neuron diseases<br />
10.00 am-10.30 am Break<br />
10.30 am-12.00 am Parallel Symposia<br />
‹Molecular basis of motor neuron diseases:<br />
insights from new mo<strong>de</strong>ls systems XSalle Endoume<br />
Chairpersons > Laurent Schaeffer and Georg Haase<br />
Don W. Cleveland, USA<br />
> ALS: a disease of motor neurons and their non-neuronal neighbors<br />
Francesco Paolo di Giorgio, USA<br />
> Interrogating disease states using embryonic stem cells: a case study in ALS<br />
Arthur Burghes, USA<br />
> A genetic approach to the critical molecular patheway in spinal muscular atrophy<br />
using zebrafish and mice<br />
Programme > Thursday, May 29<br />
‹Genetics and Biomarkers of motor neuron diseases XAmphitheatre Callelongue<br />
Chairpersons > Suzanne Lefebvre and Jean-Pierre Azulay<br />
Nazli Basak, Turkey<br />
> Genetics of ALS<br />
Pascale Saugier Veber, France<br />
> Sensitive assays for mea<strong>sur</strong>ing SMN gene copy number and mRNA in SMA patients<br />
Utz Fischer, Germany<br />
> Un<strong>de</strong>rstanding the molecular basis of spinal muscular atrophy<br />
‹Therapeutics in SMA and ALS: results and perspectives XAuditorium<br />
Chairpersons > Bertrand Fontaine and Louis Viollet<br />
Enrico Bertini, Italy<br />
> Bottlenecks in trials for SMA<br />
12.00 am-1.00 pm Lunch break<br />
Jean Pouget, France<br />
> Learning from clinical trials and standards of care in ALS<br />
Martine Barkats , France<br />
> AAV-mediated gene transfer in the central nervous system of a feline mo<strong>de</strong>l of SMA<br />
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