(R,S)-MTD - THS 10
(R,S)-MTD - THS 10
(R,S)-MTD - THS 10
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Méthadone est un médicament chiral<br />
(R)-methadone<br />
Agoniste récepteur opiacé mu<br />
IC50= 3 – 7 µM<br />
Forme active<br />
(S)-methadone<br />
Faible agoniste récepteur opiacé mu<br />
IC50 = 26 – 88 µM<br />
Forme inactive<br />
Kristensen et al., Life Sci 1995;56(2):PL45-50