(R,S)-MTD - THS 10
(R,S)-MTD - THS 10
(R,S)-MTD - THS 10
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(R,S)-<strong>MTD</strong> => (R)-<strong>MTD</strong><br />
=> Diminution du QTc<br />
QTcF, med (IQR)<br />
Day 0<br />
Day 7<br />
Day 14<br />
423 (398-440) ms<br />
418 (394-429) ms<br />
412 (395-431) ms<br />
Diminution moyenne du QTcF de<br />
-3.9ms par semaine (p=0.04)<br />
Ansermot et al., Arch Intern Med. 20<strong>10</strong>;170(6):529-536<br />
Médianes et quartiles, IC 95 %
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