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ARBEITSGEMEINSCHAFT DER INSTITUTE FÜR ... - HAL - INRIA

ARBEITSGEMEINSCHAFT DER INSTITUTE FÜR ... - HAL - INRIA

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Die Konzentration in der Hämolymphe erreichte nach 1<br />

Stunde das Maximum<br />

von 30,1 ng/yl und sank bis 4 Stunden nach der Fütterung auf 17,5 ng/yl und<br />

bis 24 Stunden auf 3,8 ng/ ld ab.<br />

Auch in Varroa-Milben war der Wirkstoff nachweisbar. Die aufgenommene<br />

Menge nahm nur innerhalb der ersten 6 Stunden zu. Zwischen 6 und 12 Stunden<br />

nach der Fütterung des Akarizids an die Biene fielen die ersten Milben ab.<br />

Apitol wird also nach orale Applikation rasch in die Hämolymphe resorbiert<br />

und auch von Milben in letalen Dosen aufgenommen. Innerhalb von 6 bis 12<br />

Stunden wird es wieder in den Darm und die Kotblase ausgeschieden.<br />

SUMMARY<br />

The distribution of a systemic acaricide in the body of the honey bee<br />

The principle of treating bees with a systemic acaricide in fighting varroatosis<br />

lies in the fact that the active ingredient is distributed throughout the bee colony<br />

through social feeding and eventually becomes absorbed from the intestinal<br />

tract into the hemolymph. In this manner it can be taken up by the Varroa mites.<br />

In order to confirm this principle, the acaricide Apitol &copy; (2-(2,4-dimethyl-phenylam<br />

ino) -3 -methyl-4 -thiazol ine-hydrochloride) was examined in individual bees which<br />

consumed 10 !Lg of this in a sugar solution.<br />

The acaricide could not be metabolized in a measurable range within the<br />

24 hours of the experiment. After 1 hour of feeding 10 jig could be found and<br />

after 4 hours, only 0,4 Itg could be found in the intestinal tracts of honey bees.<br />

Simultaneously, the acaricide accumulated exclusively in the rectum whereby<br />

3,61 jig and 8,59 IL g could be detected after 30 minutes and 6 hours, respectively.<br />

The concentration in the hemolymph reached a maximum of 30,1 ng/ [d after<br />

1 hour of feeding and sank to 17,5 ng/yl at 4 hours and finally to 3,8 ng/jd after<br />

24 hours. The active ingredient was also detectable in Varroa mites. The amount<br />

taken up increased only within the first 6 hours. The first mites fell off between 6<br />

and 12 hours after the bees fed on the acaricide. Therefore, Apitol &reg; is quickly<br />

resorbed in the hemolymph and taken up in lethal doses by the mites. It is then<br />

excreted into the intestines and the rectum.<br />

RÉSUMÉ<br />

Répartition d’un acaricide sy.stémique dans le corps de l’abeille<br />

Le principe de traiter les abeiles avec un acaricide systémique<br />

contre la<br />

varroose réside dans le fait que la substance active est distribuée dans toute la

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