29.01.2014 Views

Infections fongiques osteo articulaires - Infectiologie

Infections fongiques osteo articulaires - Infectiologie

Infections fongiques osteo articulaires - Infectiologie

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Diffusion osseuse des anti<strong>fongiques</strong><br />

Administration/<br />

Posologie<br />

Pic sérique<br />

μg /l<br />

Fongicide/statique<br />

Pénétration<br />

osseuse-liquide<br />

articulaire<br />

C os/ C plasma<br />

AMB<br />

0,5 – 1 mg /kg<br />

1,2 – 2,4<br />

Cide<br />

1-1,5<br />

IV<br />

L-AMB<br />

3 – 5 mg /kg<br />

83<br />

Cide<br />

2<br />

IV<br />

Itraconazole<br />

200 – 400 mg /J<br />

1,7<br />

Cide<br />

> 5<br />

Per os<br />

Fluconazole<br />

400 – 800 mg/j<br />

% à la posologie<br />

Cide<br />

2 – 5<br />

IV per os<br />

18mg/l (400)<br />

Voriconazole<br />

4mg / kg /12H IV ,<br />

per os<br />

1,89<br />

Cide<br />

2 – 5<br />

Posaconazole<br />

10 ml /12 H<br />

Cide<br />

2 – 5<br />

Per os<br />

9,6<br />

Caspofungine<br />

50- 70 mg /j IV<br />

Statique<br />

?<br />

Flucytosine<br />

500mg /J<br />

11,2<br />

statique<br />

> 5<br />

JPB Os Lyon 11 08

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!