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cours "exocytose" - la physiologie animale a l'universite de lille i

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8 gènes :<br />

CACNGx<br />

Structure générale <strong>de</strong>s canaux calciques<br />

voltage-dépendants<br />

Protéines γ(x = 1-8)<br />

10 gènes :<br />

CACNA1X<br />

Protéines α1 (X = A,B,C,D,E,F,G,H,I,S)<br />

4 familles <strong>de</strong> sous-unités :<br />

•α1 : pore<br />

•β, α2-δ, et γ : sous-unités accessoires<br />

4 (5?) gènes :<br />

CACNA2Dx<br />

Protéines α2δ(x = 1-5)<br />

4 gènes :<br />

CACNBx<br />

Protéines β(x = 1-4)<br />

Le Canal Ca 2+ voltage <strong>de</strong>pendant<br />

Caterall WA (1994) Auxiliary subunits of voltage-gated ion channels<br />

, Neuron 12, 1183-1194, with permission<br />

Campbell KP, Harpold MM et al. (2000) Nomenc<strong>la</strong>ture of voltagegated<br />

calcium channels, Neuron 25, 533-535, with permission.<br />

Libération hormonale<br />

Neurotransmission<br />

17

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