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Angor - Faculté de médecine Pierre et Marie Curie

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Infarctus du suj<strong>et</strong> âgé <strong>et</strong> aspirine:<br />

Medicare USA (n=10.018)<br />

• Seulement 60% <strong>de</strong>s patients > 65 ans (en l’absence <strong>de</strong><br />

contre­indication)<br />

• Patients à risque: taux inférieur!<br />

• Aspirine: eff<strong>et</strong> bénéfique indépendant RR=0.78<br />

Krumholz HM. Circulation 1995;92:2841<br />

1995;92:2841­2847<br />

Réduction <strong>de</strong> mortalité<br />

• Thrombolyse seule (GISSI 2, ISIS ISIS­2): 13­16%<br />

•Thrombolyse Thrombolyse + Aspirine (ISIS 2): 34%

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