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Inhibición de tirosinasa y melanina en melanocitos humanos normales

IN VITRO

LUMISKIN (%)

(eq DAB ppm)

% inhibition / control

0

-10

-20

-30

-40

-50

-60

-70

1.25% 2.5% 3.7% 0.06%

12,5 25 37 600ppm

Tirosinasa

Melanina

Acido kójico

La actividad inhibidora de la DAB sobre la tirosinasa es dosisdependiente.

Se requiere una cantidad de ácido kójico 15 veces mayor para alcanzar el

mismo invel de inhibición.

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