[Wade L.G.] - Química Orgánica Tomo 1

A 2 0
Apéndices
APÉNDICE 5 Valores d e pKa para los com puestos representativos
Compuesto
pKa
Compuesto P*a Compuesto pKa
Y 7 N
/ +\
H H
8 .0
H2NNH3 8 .1
O
II
c h 3c o o h 8 .2
c h 3c h 2n o 2 8 .6
0 0
lí II
CH3CCHoCCH3 8.9
Or>
w H
8.9
H C = N 9.1
A
/ \
H
H
c l A _ / - OH
NH4
h o c h 2c h 2n h 3
o
+ II
h 3n c h 2c o -
\ /
-OH
CH3CH2SH
(CH3)3NH
o o
II II
CH3CCH2COEt
9.3
9.4
9.4
9.5
9.8
10.0
10.2
10.2
10.2
10.3
10.5
10.6
10.7
(CH3)2NH2
NH,
c h 3c h 2ñ h 3
> N '
/ \
H H
O >1-3
+N
/ \
H H
HPO4 - 12.3
CF3CH2OH 12.4
O O
II II
EtOCCH2COEt 13.3
H C = C C H 2OH 13.5
O
II
H2NCNH2 13.7
CH3
+l
CH3NCH2CH2OH 13.9
CH3
r = \
NV NH
14.4
CH3OH 15.5
H20 15.7
CH3CH2OH 15.9
O
II
CH3CNH2
o
o
O
16
CCH3 16.0
O
10.7 II
c h 3c h
(CH3)3COH
10.7
O
II
10.7 c h 3c c h 3
11.1
-1 7
17
18
2 0
0
II
CH3COEt 24.5
H C = C H 25
CH 3C = N 25
O
II
CH 3CN(CH 3) 2
n h 3
Q H
CH 3NH2
0 ^ c h 3
w
CH 2= C H C H 3
c h , = c h 2
V
c h 4
c h 3c h 3
30
36
36
40
41
43
43
44
46
50
50
CH3NH3
10.7