Sindrome.del.Ovario.Poliquistico

42 Síndrome del Ovario Poliquístico
androgenism. J Clin Endocrinol Metab.
2002;87:3977-83.
124
Villuendas G, San Millán JL, Sancho J,
Escobar-Morreale HF. The -597 G->A
and -174 G->C polymorphisms in the
promoter of the IL-6 gene are associated
with hyperandrogenism. J Clin
Endocrinol Metab. 2002;87:1134-41.
125
Walch K, Grimm C, Zeillinger R, Huber
JC, Nagele F, Hefler LA. A common
interleukin-6 gene promoter polymorphism
influences the clinical characteristics
of women with polycystic
ovary syndrome. Fertil Steril. 2004;81:
1638-41.
126
Escobar-Morreale HF, Calvo RM,
Villuendas G, Sancho J, San Millán JL.
Association of polymorphisms in the
interleukin 6 receptor complex with
obesity and hyperandrogenism. Obes
Res. 2003;11:987-96.
127
Hoffstedt J, Andersson IL, Persson
L, Isaksson B, Arner P. The common
-675 4G/5G polymorphism in the plasminogen
activator inhibitor -1 gene is
strongly associated with obesity. Diabetologia.
2002;45:584-7.
128
Diamanti-Kandarakis E, Palioniko G,
Alexandraki K, Bergiele A, Koutsouba
T, Bartzis M. The prevalence of 4G5G
polymorphism of plasminogen activator
inhibitor-1 (PAI-1) gene in polycystic
ovarian syndrome and its association
with plasma PAI-1 levels. Eur J Endocrinol.
2004;150:793-8.
129
Diamanti-Kandarakis E, Kouli CR, Bergiele
AT, et al. A survey of the polycystic
ovary syndrome in the Greek island of
Lesbos: hormonal and metabolic profile.
J Clin Endocrinol Metab. 1999;84:
4006-11.
130
Azziz R, Woods KS, Reyna R, Key TJ,
Knochenhauer ES, Yildiz BO. The prevalence
and features of the polycystic
ovary syndrome in an unselected population.
J Clin Endocrinol Metab. 2004;
89:2745-9.
131
Fernández-Real JM, Ricart W. Insulin
resistance and inflammation in an
evolutionary perspective: the contribution
of cytokine genotype/phenotype
to thriftiness. Diabetologia. 1999;42:
1367-74.
132
Witchel SF, Lee PA, Suda-Hartman M,
Trucco M, Hoffman EP. Evidence for a
heterozygote advantage in congenital
adrenal hyperplasia due to 21-hydroxylase
deficiency. J Clin Endocrinol
Metab. 1997;82:2097-101.
133
Parsons P. Success in mating: a coordinated
approach to fitness through genotypes
incorporating genes for stress
resistance and heterozygous advantage
under stress. Behav Genet. 1997;27:
75-81.
134
Stearns SC, Ackermann M, Doebeli M,
Kaiser M. Experimental evolution of
aging, growth, and reproduction in fruitflies.
Proc Natl Acad Sci USA. 2000;97:
3309-13.