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O papel modulador do gene AIRE - capes

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MANUSCRITOBruno R, Sabater L, Tolosa E, et al. Different patterns of nicotinic acetylcholinereceptor subunit transcription in human thymus. J Neuroimmunol 2004;149:147–59.Gallegos AM, Bevan MJ (2006). Central tolerance: good but imperfect.Immunol Rev. 209: 290-6.Basso K, Margolin AA, Stolovitzky G, Klein U, Dalla-Favera R, Califano A(2005) Reverse engineering of regulatory networks in human B cells. NatGenet 37: 382-390Margolin A, Nemenman I, Basso K, Wiggins C, Stolovitzky G, Della Favera R,Califano A (2006) Aracne: an algorithm for the reconstruction of <strong>gene</strong>regulatory networks in a mammalian cellular context. BMC BioinformaticsS1Gardner T, di Bernar<strong>do</strong> D, Lorenz D, Collins J (2003) Infering <strong>gene</strong>tic networksand identifying compound mode of action via expression profiling. Science301: 102-105Di Bernar<strong>do</strong> D, Thomson M, Gardner T, Chobot S, Eastwood E, Wojtovich A,Elliott S, Schaus S, Collins J (2005) Chemogenomic profiling on agenome-wide scale using reverse-engineered <strong>gene</strong> networks. Nat.Biotechnol. 23; 377-383Bansal M, Della Gatta G, di Bernar<strong>do</strong> D (2006) Inference of <strong>gene</strong> regulatorynetworks and compound mode of action from time course <strong>gene</strong> expressionprofiles. Bioinformatics 22: 815-822Yu J, Smith VA, Wang PP, Hartemink AJ, Jarvis ED (2004) Advances toBayesian network inference for <strong>gene</strong>rating causal networks fromobservational biological data. Bioinformatics 20: 3594-3603219

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