O papel modulador do gene AIRE - capes

MANUSCRITOPromiscuous gene expression is connected in networkPromiscuous gene expression in medullary thymic epithelialcells is connected in network where the Aire gene is anupstream modulatorClaudia Macedo 1 , Thaís A. Fornari 1 , Danielle A. R. Magalhães 1 ,Cristina M. Junta 1 , Guilherme L. Silva 1 , Leandra L. Linhares 2 ,Wilson Savino 2 , Elza T. Sakamoto-Hojo 1 , Eduardo A. Donadi 4 ,Geraldo A. S. Passos 1,31) Molecular Immunogenetics Group, Department of Genetics, Facultyof Medicine of Ribeirão Preto, University of São Paulo (USP),Ribeirão Preto, SP, Brazil.2) Laboratory on Thymus Research, Department of Immunology,Oswaldo Cruz Institute (FIOCRUZ), Rio de Janeiro, RJ, Brazil.3) Discipline of Genetics, Faculty of Dentistry of Ribeirão Preto, USP,Ribeirão Preto, SP, Brazil.4) Division of Clinical Immunology, Faculty of Medicine of RibeirãoPreto, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.Send correspondence to: Dr. Geraldo A. S. PassosMolecular Immunogenetics Group, Department of Genetics, Faculty ofMedicine of Ribeirão Preto, University of São Paulo (USP), ViaBandeirantes, 3900 ZIP CODE: 14040-900, Ribeirão Preto, SP, Brazil.Tel. +55 16 3602 3030 Fax +55 16 3633 0069 E-mailpassos@rge.fmrp.usp.br202