O papel modulador do gene AIRE - capes

ANEXO IITabela III. Genes diferencialmente expressos comparando-se células mTEC controles versus células mTEC transfectadas com RNAianti-Aire (FDR 15%, p-value 0,015).Gene Symbol CloneID Gene Name Fold change q-value (%)EST IMAGE:640598 Expressed sequence tag 1.0673177 14.5946665EST IMAGE:640817 Expressed sequence tag 1.091488 14.5946665Gclm IMAGE:639968 Glutamate-cysteine ligase , modifier subunit 1.1114856 12.903029EST IMAGE:640144 Expressed sequence tag 1.0997492 12.903029E2f2 IMAGE:640754 E2F transcription factor 2 1.1284692 12.903029IMAGE:1225768 Apoptosis-inducing, TAF9-like domain 1 1.06998 12.9030292610040C18RikEST IMAGE:640272 Expressed sequence tag 1.1294833 12.903029EST IMAGE:640451 Expressed sequence tag 1.0881842 12.903029EST IMAGE:583312 Expressed sequence tag 1.0601645 12.903029EST IMAGE:639827 Expressed sequence tag 1.1019533 12.085992Myg1 IMAGE:583514 Melanocyte proliferating gene 1 1.1121532 12.085992Gamma-aminobutyric acid (GABA-A) receptor-associated proteinlike2 1.0723306 12.085992Klhl7IMAGE:583190Sh3d1B IMAGE:583881 Intersectin 2 1.0822399 12.085992EST IMAGE:640792 Expressed sequence tag 1.0899262 12.085992Epc1 IMAGE:583089 Enhancer of polycomb homolog 1 (Drosophila) 1.1037792 12.085992AI452102 IMAGE:639804 RIKEN cDNA E230029C05 gene 1.0712574 12.085992Txnrd1 IMAGE:583921 Thioredoxin reductase 1 1.0930426 12.085992EST IMAGE:583308 Expressed sequence tag 1.0649359 12.085992EST IMAGE:641140 Expressed sequence tag 1.0681186 12.085992EST IMAGE:640351 Expressed sequence tag 1.1232543 12.0859921110008H02Rik IMAGE:640371 Transcribed locus 1.0701028 12.085992H13 IMAGE:640912 Histocompatibility 13 1.0737796 12.085992EST IMAGE:640865 Expressed sequence tag 1.1486661 12.085992186