O papel modulador do gene AIRE - capes
O papel modulador do gene AIRE - capes O papel modulador do gene AIRE - capes
ANEXO ITranscribed locusTranscribed locus, moderately similar toIMAGE:582892XP_001103164.1 similar to 60S ribosomalprotein L12 [Macaca mulatta] 0.17361486 0.40003896 1.51EST IMAGE:583695 Expressed sequence tag 0.1608681 0.4003079 1.51Eif2a IMAGE:582939 Eukaryotic translation initiation factor 2a 0.15705606 0.40112728 1.37Ccdc58 IMAGE:582929 Coiled-coil domain containing 58 0.18879382 0.4011698 1.37Btg2 IMAGE:639859 B-cell translocation gene 2, anti-proliferative 0.22523461 0.4013058 1.37Taf15IMAGE:639860TAF15 RNA polymerase II, TATA boxbinding protein (TBP)-associated factor 0.24421383 0.4013146 1.37EST IMAGE:583906 Expressed sequence tag 0.2946352 0.40145835 1.37In multiple clusters IMAGE:641096 Expressed sequence tag 0.2501315 0.40156463 1.37Uqcrfs1IMAGE:640752Ubiquinol-cytochrome c reductase, Rieskeiron-sulfur polypeptide 1 0.101116255 0.40176198 1.37Dhrs13IMAGE:576046Dehydrogenase/reductase (SDR family)member 13 0.11375762 0.4019725 1.37Fyb IMAGE:1264938 Prohibitin 0.17272258 0.40204743 1.37Rpain IMAGE:573267 RPA interacting protein 0.13627423 0.40244517 1.372500002K03RikIMAGE:583524CDNA, clone:Y0G0124L21,strand:unspecified 0.086820185 0.40269917 1.37Trim17 IMAGE:1263520 Transcribed locus 0.15638469 0.40282822 1.37Bid IMAGE:640130 BH3 interacting domain death agonist 0.1461156 0.40290505 1.37Clec14a IMAGE:576574 C-type lectin domain family 14, member a 0.21469185 0.40293807 1.37Arpc3 IMAGE:640677 Actin related protein 2/3 complex, subunit 3 0.2750277 0.40315855 1.37EST IMAGE:640868 Expressed sequence tag 0.2505796 0.40386733 1.37EST IMAGE:640319 Expressed sequence tag 0.38339138 0.404027 1.37EST IMAGE:583103 Expressed sequence tag 0.33644107 0.4041983 1.37EST IMAGE:640173 Expressed sequence tag 0.1080738 0.4047628 1.26C77370 IMAGE:583793 Expressed sequence C77370 0.19215246 0.40533575 1.265330438D12Rik IMAGE:640084 RIKEN cDNA 5330438D12 gene 0.17964597 0.40572393 1.26EST IMAGE:583673 Expressed sequence tag 0.1918779 0.40591183 1.26ArntlIMAGE:582931Aryl hydrocarbon receptor nucleartranslocator-like 0.21954234 0.4060044 1.26135
ANEXO ITranscribed locus IMAGE:640397 Transcribed locus 0.19581184 0.4068279 1.261700106N22Rik IMAGE:640218 RIKEN cDNA 1700106N22 gene 0.21035998 0.4069919 1.26EST IMAGE:583595 Expressed sequence tag 0.34630018 0.4074916 1.261810059G22Rik IMAGE:583234 RIKEN cDNA 1810059G22 gene 0.2897901 0.40794325 1.18EST IMAGE:583474 Expressed sequence tag 0.29084098 0.40822262 1.18Grcc10 IMAGE:641036 Atrophin 1 0.25110045 0.40835306 1.18Chchd1IMAGE:583655Coiled-coil-helix-coiled-coil-helix domaincontaining 1 0.3520113 0.40859562 1.18Kctd10IMAGE:640583Potassium channel tetramerisation domaincontaining 10 0.40539417 0.4089895 1.18AI194318IMAGE:5832763 days neonate thymus cDNA, RIKEN fulllengthenriched library, clone:A630066K17product:unclassifiable, full insert sequence 0.17482738 0.4091023 1.18Stat1IMAGE:583302Signal transducer and activator of transcription1 0.048201974 0.40922952 1.18EST IMAGE:640849 Expressed sequence tag 0.12987265 0.4096255 1.18Transcribed locus IMAGE:583764 Transcribed locus 0.090552844 0.4096824 1.18CXCL10 IMAGE:2069299 Chemokine (C-X-C motif) ligand 10 0.17077018 0.41001084 1.18EST IMAGE:582106 Expressed sequence tag 0.28126255 0.4101807 1.18Mbnl1 IMAGE:583553 Muscleblind-like 1 (Drosophila) 0.19088008 0.41020763 1.18Transcribed locus IMAGE:640052 Similar to ariadne homolog 2 0.24588272 0.410971 1.18Atp5c1IMAGE:640931ATP synthase, H+ transporting,mitochondrial F1 complex, gammapolypeptide 1 0.42529702 0.41185647 1.07EG666113 IMAGE:641052 Predicted gene, EG666113 0.10545162 0.4122206 1.07Amica1IMAGE:640276Adhesion molecule, interacts with CXADRantigen 1 0.18005581 0.41252714 1.07Ltb IMAGE:577871 Lymphotoxin B 0.23434414 0.41267005 1.07Tcrg-C IMAGE:640129 T-cell receptor gamma, constant region 0.10797722 0.41389433 1.07EST IMAGE:639831 Expressed sequence tag 0.16276084 0.4139148 1.07Anks1bIMAGE:573163Ankyrin repeat and sterile alpha motif domaincontaining 1B 0.112788066 0.41394684 1.07136
- Page 100 and 101: RESULTADOSFigura 26. Gráfico ilust
- Page 102 and 103: RESULTADOS6.8. Influência do silen
- Page 104 and 105: Discussão
- Page 106 and 107: DISCUSSÃOA tolerância do repertó
- Page 108 and 109: DISCUSSÃOCom relação à técnica
- Page 110 and 111: DISCUSSÃOgene AIRE (do inglês aut
- Page 112 and 113: DISCUSSÃOdesse modo a tolerância
- Page 114 and 115: DISCUSSÃOPML (leucemia promielocit
- Page 116 and 117: DISCUSSÃOBoehm et al. (2003) afirm
- Page 118 and 119: DISCUSSÃOprograma Genenetwork (Wu
- Page 120 and 121: Conclusões
- Page 122 and 123: Referências Bibliográficas
- Page 124 and 125: REFERÊNCIAS BIBLIOGRÁFICASBarthlo
- Page 126 and 127: REFERÊNCIAS BIBLIOGRÁFICASDissert
- Page 128 and 129: REFERÊNCIAS BIBLIOGRÁFICASGotter
- Page 130 and 131: REFERÊNCIAS BIBLIOGRÁFICASMatsumo
- Page 132 and 133: REFERÊNCIAS BIBLIOGRÁFICASby mito
- Page 134 and 135: REFERÊNCIAS BIBLIOGRÁFICASRossi S
- Page 136 and 137: REFERÊNCIAS BIBLIOGRÁFICASof thym
- Page 138 and 139: Anexo I123
- Page 140 and 141: ANEXO IEST IMAGE:582370 Expressed s
- Page 142 and 143: ANEXO IDhps IMAGE:583332 Deoxyhypus
- Page 144 and 145: ANEXO IMapkapk2 IMAGE:572979 MAP ki
- Page 146 and 147: ANEXO IGm608 IMAGE:583350 Gene mode
- Page 148 and 149: ANEXO ICcdc72 IMAGE:640628 Coiled-c
- Page 152 and 153: ANEXO IEST IMAGE:583221 Expressed s
- Page 154 and 155: ANEXO ITranscribed locusTranscribed
- Page 156 and 157: ANEXO Irepair deficiency, complemen
- Page 158 and 159: ANEXO Imember 1EST IMAGE:583824 Exp
- Page 160 and 161: ANEXO ITranscribed locus IMAGE:5830
- Page 162 and 163: ANEXO ITfdp1 IMAGE:640119 Transcrib
- Page 164 and 165: ANEXO IEST IMAGE:583902 Expressed s
- Page 166 and 167: ANEXO I2410022M11Rik IMAGE:640727 R
- Page 168 and 169: ANEXO Icontaining 1Kif14 IMAGE:5836
- Page 170 and 171: ANEXO Imember 3In multiple clusters
- Page 172 and 173: ANEXO IEST IMAGE:639632 Expressed s
- Page 174 and 175: ANEXO IAnkrd10 IMAGE:583740 Ankyrin
- Page 176 and 177: ANEXO IEST IMAGE:641035 Expressed s
- Page 178 and 179: ANEXO IVcam1 IMAGE:576563 Vascular
- Page 180 and 181: ANEXO ITegt IMAGE:639877 Testis enh
- Page 182 and 183: ANEXO I3Ehmt2Euchromatic histone ly
- Page 184 and 185: ANEXO IEST IMAGE:583217 Expressed s
- Page 186 and 187: ANEXO IEST IMAGE:640851 Expressed s
- Page 188 and 189: ANEXO I20 homolog (yeast)Ube1c IMAG
- Page 190 and 191: ANEXO IRasa3 IMAGE:582174 RAS p21 p
- Page 192 and 193: ANEXO IEST IMAGE:640642 Expressed s
- Page 194 and 195: ANEXO I4930566A11Rik IMAGE:583433 R
- Page 196 and 197: ANEXO IEST IMAGE:640824 Expressed s
- Page 198 and 199: ANEXO IEST IMAGE:582998 Expressed s
ANEXO ITranscribed locus IMAGE:640397 Transcribed locus 0.19581184 0.4068279 1.261700106N22Rik IMAGE:640218 RIKEN cDNA 1700106N22 <strong>gene</strong> 0.21035998 0.4069919 1.26EST IMAGE:583595 Expressed sequence tag 0.34630018 0.4074916 1.261810059G22Rik IMAGE:583234 RIKEN cDNA 1810059G22 <strong>gene</strong> 0.2897901 0.40794325 1.18EST IMAGE:583474 Expressed sequence tag 0.29084098 0.40822262 1.18Grcc10 IMAGE:641036 Atrophin 1 0.25110045 0.40835306 1.18Chchd1IMAGE:583655Coiled-coil-helix-coiled-coil-helix <strong>do</strong>maincontaining 1 0.3520113 0.40859562 1.18Kctd10IMAGE:640583Potassium channel tetramerisation <strong>do</strong>maincontaining 10 0.40539417 0.4089895 1.18AI194318IMAGE:5832763 days neonate thymus cDNA, RIKEN fulllengthenriched library, clone:A630066K17product:unclassifiable, full insert sequence 0.17482738 0.4091023 1.18Stat1IMAGE:583302Signal transducer and activator of transcription1 0.048201974 0.40922952 1.18EST IMAGE:640849 Expressed sequence tag 0.12987265 0.4096255 1.18Transcribed locus IMAGE:583764 Transcribed locus 0.090552844 0.4096824 1.18CXCL10 IMAGE:2069299 Chemokine (C-X-C motif) ligand 10 0.17077018 0.41001084 1.18EST IMAGE:582106 Expressed sequence tag 0.28126255 0.4101807 1.18Mbnl1 IMAGE:583553 Muscleblind-like 1 (Drosophila) 0.19088008 0.41020763 1.18Transcribed locus IMAGE:640052 Similar to ariadne homolog 2 0.24588272 0.410971 1.18Atp5c1IMAGE:640931ATP synthase, H+ transporting,mitochondrial F1 complex, gammapolypeptide 1 0.42529702 0.41185647 1.07EG666113 IMAGE:641052 Predicted <strong>gene</strong>, EG666113 0.10545162 0.4122206 1.07Amica1IMAGE:640276Adhesion molecule, interacts with CXADRantigen 1 0.18005581 0.41252714 1.07Ltb IMAGE:577871 Lymphotoxin B 0.23434414 0.41267005 1.07Tcrg-C IMAGE:640129 T-cell receptor gamma, constant region 0.10797722 0.41389433 1.07EST IMAGE:639831 Expressed sequence tag 0.16276084 0.4139148 1.07Anks1bIMAGE:573163Ankyrin repeat and sterile alpha motif <strong>do</strong>maincontaining 1B 0.112788066 0.41394684 1.07136
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